Browsing by Title
Now showing items 810-829 of 1816
-
Identification and cross-species amplification of microsatellite markers derived from expressed sequence data of rose species
(Springer India, 2015)Genic SSR markers derived from public expressed sequence tags (ESTs) data are valuable and cost effective marker resources for genome mapping and diversity studies. Owing to their derivation from the transcribed regions ... -
Identification of Curcuma longa phytochemicals as a novel inhibitor of proteins involved in Allergic Rhinitis
(Central University of Punjab, 2018)Histamine and other chemical mediators play crucial role in the disease development condition of allergic rhinitis. Allergic rhinitis is a mild or severe allergic condition due to the interaction of allergens with the IgE ... -
Identification Of Ganoderic Acids And Derivatives From Fruiting Bodies Of Ganoderma Lucidum
(Central University of Punjab, 2018)Ganoderic acids and other bioactive triterpene metabolites from crude extract of wood decaying fungus Ganoderma lucidum from two different hosts Acacia and Azadirachta were to be isolated as proposed. The method for ... -
Identification of natural inhibitors of proteins involved in the pathology of Parkinson's disease
(Central University of Punjab, 2018)Parkinson's disease (PD) is a progressive neurodegenerative disorder caused due to the lack of dopamine in the brain. Different drug therapies are available for PD showing excellent efficiency, but most of them are cost ... -
Identification of new insulin growth factor receptor-1 (IGF-1R) inhibitors via exploring ATPas kinase domain of IGF-1R through virtual screening
(Birkhauser Boston, 2017)Insulin growth factor receptor-1 is a trans-membrane tyrosine kinase receptor that mediates the polypeptide protein hormone insulin growth factor-1, responsible for normal function and growth of human cells. The overexpression ... -
Identification of novel indole based heterocycles as selective estrogen receptor modulator
(Academic Press Inc., 2018)In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II ... -
Identification of novel indole based heterocycles as selective estrogen receptor modulator.
(Elsevier, 2018)In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II ... -
Identification of Novel lncRNA in Breast Cancer Cell Line
(Central University of Punjab, 2018)Long non-coding RNA(lncRNA) is RNA transcript having size of more 200 nucleotides and low number of exons are present due to which it expressed at lower level in specific tissues. Mainly the lncRNA is involved in gene ... -
Identification of Novel Natural Inhibitors Of Proteins Involved In Cancer Cell Stemness
(Central University of Punjab, 2018)Cancer stem cells (CSCs) are a small subpopulation of cells identified in a variety of tumors that are capable of self-renewal, differentiation and have the unique property to evade radiotherapy and chemotherapy. CSCs are ... -
Identification of novel translocation between short arm of chromosome 4 and long arm of chromosome 6 in an infertile man using Interphase Chromosome Profiling (ICP)
(Blackwell Publishing Ltd, 2018)Conventional cytogenetics has always been a favourite to detect chromosomal aberrations. Carriers of chromosomal translocation are often phenotypically normal but are infertile. Couples are often advised to go for karyotyping, ... -
Identification of potential natural inhibitors of SARS-CoV2 main protease by molecular docking and simulation studies
(Taylor and Francis Ltd., 2020)Coronaviruses are contagious pathogens primarily responsible for respiratory and intestinal infections. Research efforts to develop antiviral agents against coronavirus demonstrated the main protease (Mpro) protein may ... -
Identification of some novel natural inhibitors of proteins in the life cycle of the malarial parasite
(Central University of Punjab, 2018)Antimalarial phytoconstituents were identified and analysed.We studied receptor based molecular docking of protein drug targets( Plasmepsin 2 (1lf2),HSP90 (3k60), PfATPase ( 1u5n), Human orotidine 5 - decarboxylase domain ... -
Identifying novel miRNA targets of anticancer drugs in normoxic and hypoxic condition
(Central University of Punjab, 2018)Breast cancer has become the prevailing cause of death, so the research for their treatment has become advanced day by day. Breast cancer behaves differently in normoxic and hypoxic condition so does the anticancer drugs ... -
Identifying the preferred interaction mode of naringin with gold nanoparticles through experimental, DFT and TDDFT techniques: Insights into their sensing and biological applications
(Royal Society of Chemistry, 2016)In this work, the binding behaviour of naringin-a flavonoid with AuNPs is explained by combining experimental and theoretical approaches. We have systematically analysed the effect of temperature and concentration of ... -
An illustrated review on cultivation and life history of agronomically important seaplants
(Nova Science Publishers, Inc., 2014)Seaplants (a better alternative to the misnomer "Seaweeds"), by all means, are "future plants"; they have been projected as the future viand for ever-increasing human populations, viable and sustainable source for biofuel ... -
Imidazole based compunds: Synethesis and in vitro anticancer screening
(Central University of Punjab, 2013)Imidazole is an important five-membered aromatic heterocycle widely present in natural products and synthetic molecules. The unique structural feature of imidazole ring with desirable electron rich characteristic is ... -
Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis
(2013)Cystatin 9 (CST9) is a member of the type 2 cysteine protease inhibitor family, which has been shown to have immunomodulatory effects that restrain inflammation, but its functions against bacterial infections are unknown. ... -
Impact Assessment Of Judicial Approach Towards Tender Process In India
(Central University of Punjab, 2018)With the growth of population the need for infrastructural and other development has also arisen much and it has created an over burdened responsibility upon the government. Thus, the government had in order to come out ...