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Now showing items 1289-1308 of 3506
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From 2011 to 2022: The development of pyrazole derivatives through the ?,?-unsaturated carbonyl compounds
(HeteroCorporation, 2023-11-25)The synthesis of pyrazole derivative using ?,?-unsaturated carbonyl compounds has attracted increasing attention of the synthetic organic chemist community. Interestingly, the simplicity of the synthetic method, high ... -
From Tradition to Troubles: Evaluating the Consumption of Opium as Social Practice in Western Rajasthan
(Ashdin Publishing, 2023-05-30)Drug consumption is not always associated solely with pleasure or intoxication; it can originate as a customary practice and evolve into a societal tradition over successive generations. In Rajasthan, particularly in its ... -
Frontal Changes of Gangotri Glacier, Garhwal Himalaya, between 1935 and 2022
(Springer, 2023-02-07)Gangotri Glacier is one of the most thoroughly investigated glaciers in the Indian Himalaya in terms of terminus monitoring. This study aims to update the frontal retreat of Gangotri Glacier between 1935 and 2022 using a ... -
Frontier tribes and nation states: infrastructural intersection at the Indo (Naga)-Myanmar borderland
(Routledge, 2020-12-11)Frontier tribes, inhabiting the Indo (Naga)-Myanmar border, are at the fringe of the nation-states. They remain outside the radar of connectivity and development. The international boundary line demarcated during the ... -
Fruit waste (peel) as bio-reductant to synthesize silver nanoparticles with antimicrobial, antioxidant and cytotoxic activities
(University of South Bohemia, 2018)Since last decade, biogenic synthesis of metal or metal-oxide nanoparticles is emerging as an alternative method, which is environment friendly, simple and safe to use. In this article, fruit waste (peel) extract (FWE) of ... -
FTIR based approach to study EnaC mechanosensory functions
(Elsevier Ltd, 2021-07-19)The pulmonary epithelial sodium ion channel (ENaC) is gaining importance for its sodium gating and mechanosensitive roles. The mechano functional studies on ENaC suggest direct molecular interactions between the ENaC protein ... -
Functional characterization of microbes and their association with unwanted substance for wastewater treatment processes
(Elsevier Ltd, 2023-07-06)Nowadays, microorganisms can be used to eliminate a variety of pollutants such as toxic metal ions from wastewater. These emergences of harmful elements in wastewater, high-priced cultivation of microbes and technical ... -
Functional characterization of microbes and their association with unwanted substance for wastewater treatment processes
(Elsevier Ltd, 2023-07-06)Nowadays, microorganisms can be used to eliminate a variety of pollutants such as toxic metal ions from wastewater. These emergences of harmful elements in wastewater, high-priced cultivation of microbes and technical ... -
Functional implications of the CpG island methylation in the pathogenesis of celiac disease
(Springer Science and Business Media B.V., 2022-05-28)Investigation of gene-environment cross talk through epigenetic modifications led to better understanding of the number of complex diseases. Clinical heterogeneity and differential treatment response often contributed by ... -
Fundamentals of Batteries and Supercapacitors: An Overview
(CRC Press, 2021-09-06)Energy plays an important role in daily human life and is the basic need in the present scenario. Nowadays, the development of energy sources is linked with the development of human civilization. The high energy density ... -
Fused Pyrimidine-Based Drug Discovery
(Elsevier, 2022-10-14)Fused Pyrimidine-Based Drug Discovery covers all categories of fused-pyrimidines along with pharmacological and in silico studies. It covers the chemistry and biological activities, as well as the design of novel ... -
Galangin, as a Potential Anticancer Agent
(Springer Science and Business Media Deutschland GmbH, 2022-04-07)Cancer is a major global health issue and one of the main causes of mortality worldwide. In recent years, cancer mortality and morbidity rates have risen dramatically due to variety of factors. Despite therapeutic alternatives, ... -
Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets
(SAGE Publications Inc., 2021-12-14)With the dramatic increase in cancer incidence all over the world in the last decades, studies on identifying novel efficient anti-cancer agents have been intensified. Historically, natural products have represented one ... -
Gametogenic and steroidogenic action of kisspeptin-10 in the Asian catfish, Clarias batrachus: Putative underlying mechanistic cascade
(Elsevier Inc., 2021-06-28)Unlike mammals, two kisspeptins genes encoding, kiss1 and kiss2 are detected in fishes with highly varied and contradictory difference in their reproductive activities. The present study was undertaken to examine the direct ... -
Ganoderic Acid A Targeting ?-Catenin in Wnt Signaling Pathway: In Silico and In Vitro Study
(Springer Berlin Heidelberg, 2018)Wnt signaling pathways are the group of signaling transduction controlling the embryonic development, cell proliferation, cell migration, cell fate specification, and body axis pattern. Nuclear accumulation of ?-catenin ... -
Ganoderic Acid A Targeting β-Catenin in Wnt Signaling Pathway: In Silico and In Vitro Study
(Springer, 2016)Wnt signaling pathways are the group of signaling transduction controlling the embryonic development, cell proliferation, cell migration, cell fate specification, and body axis pattern. Nuclear accumulation of β-catenin ... -
Ganoderic acid modulating TNF and its receptors: in silico and in vitro study
(Springer, 2017)Cancer is a multifactorial disease with a network of genes causing genetic alterations. The sophisticated techniques in molecular biology revealed different cancer pathway, but their mechanistic approach is still shrouded. ... -
Ganoderic acid targeting multiple receptors in cancer: in silico and in vitro study
(Springer Netherlands, 2016)Receptor tyrosine kinases (RTKs) are transmembrane high-affinity surface receptors responsible for cell migration, adhesion, apoptosis, metabolism, and cell proliferation activities in various cancers. Minute aberration ... -
Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer
(Sage, 2017)Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and ... -
Ganoderic acid, lanostanoid triterpene: a key player in apoptosis
(Springer New York LLC, 2018)Cancer is a multifactorial disease, causing behavioral and metabolic alterations, leading to uncontrolled cell proliferation with collateral weakening of immune system. Crucial balance between cell proliferation and cell ...