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Now showing items 2025-2044 of 3506
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Molecular docking and in vitro study of Syzygium cumini-derived natural compounds on receptor tyrosine kinases pathway components
(Inderscience Enterprises Ltd., 2019)Syzygium cumini (S. cumini) is used for a variety of biological activities such as anti-inflammatory, anti-diabetic and anti-oxidant; currently, it has been reported for DNA protecting activity against radiation damage. ... -
Molecular docking simulation study of phytoestrogens asparagus racemosus in breast cancer progression
(International Journal Of Pharmaceutical Sciences And Research (IJPSR), 2015)Phytoestrogens are the xenoestrogens which are derived from the plant. This is the first report providing the deeper inside into the mechanism involved in restricting breast cancer progression with the help of docking ... -
Molecular docking study of asafoetida phytoconstituents as 14?-demethylase and transpeptidase inhibitors
(Nova Science Publishers, Inc., 2022-11-24)Asafoetida, an oleo gum resin obtained from Ferula asafoetida of medicinal and nutritional importance. It has been traditionally used for the treatment of various ailments as spice and medicine from centuries. A number of ... -
Molecular docking study of natural alkaloids as multi-targeted hedgehog pathway inhibitors in cancer stem cell therapy.
(Elsevier, 2015)Cancer is responsible for millions of deaths throughout the world every year. Increased understanding as well as advancements in the therapeutic aspect seems suboptimal to restrict the huge deaths associated with cancer. ... -
Molecular Docking Study of Natural Compounds against Non Receptor Protein Tyrosine Kinases Src
(Pharma Scholars Library, 2015)Non-receptor tyrosine kinases Src family plays an important role in signal transduction induced by diverse extracellular stimulus, including cytokine, and growth factors. Overactivity or overexpression of the non-receptor ... -
Molecular docking, 3D-QSAR and simulation studies for identifying pharmacophoric features of indole derivatives as 17?-hydroxysteroid dehydrogenase type 5 (17?-HSD5) inhibitors
(Taylor and Francis Ltd., 2023-02-06)Excess of androgens leads to various diseases such as Poly-Cystic Ovarian Syndrome, Prostate Cancer, Hirsutism, Obesity and Acne. 17?-Hydroxysteroid Dehydrogenase type 5 (17?-HSD5) converts androstenedione into testosterone ... -
Molecular dynamics and 3D-QSAR studies on indazole derivatives as HIF-1? inhibitors
(Taylor and Francis Ltd., 2022-03-23)Hypoxia-inducible factor (HIF) is a transcriptional factor which plays a crucial role in tumour metastasis thereby responsible for development of various forms of cancers. Indazole derivatives have been reported in the ... -
Molecular Mechanism of Beneficial Effects of Probiotics in Alcohol-Induced Liver Disorder
(Springer Nature, 2022-05-04)Regular consumption of alcohol remains a predominant cause of a variety of hepatic disorders. There exist many alcohol-induced liver diseases including steatosis, steatohepatitis, and cirrhosis. Microflora of the gut has ... -
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis
(Springer Science and Business Media Deutschland GmbH, 2022-11-28)ROS include hydroxyl radicals (HO.), superoxide (O2.), and hydrogen peroxide (H2O2). ROS are typically produced under physiological conditions and play crucial roles in living organisms. It is known that ROS, which are ... -
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement
(Academic Press, 2020)Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid that has the potential to affect human ... -
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement
(Academic Press, 2020-05-24)Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid that has the potential to affect human ... -
Molecular mechanisms of action of genistein in cancer: Recent advances
(Frontiers Media S.A., 2019)Background: Genistein is one among the several other known isoflavones that is found in different soybeans and soy products. The chemical name of genistein is 4?,5,7-trihydroxyisoflavone. Genistein has drawn attention of ... -
Molecular mechanisms of action of tocotrienols in cancer: Recent trends and advancements
(MDPI AG, 2019)Tocotrienols, found in several natural sources such as rice bran, annatto seeds, and palm oil have been reported to exert various beneficial health promoting properties especially against chronic diseases, including cancer. ... -
Molecular mechanisms of alcohol's effects on the human body: A review and update
(John Wiley and Sons Inc, 2023-08-14)Alcohol consumption has been linked to numerous negative health outcomes although it has some beneficial effects on moderate dosages, the most severe of which being alcohol-induced hepatitis. The number of people dying ... -
Molecular phylogeography of Ficus benghalensis Linnaeus using nrDNA ITS 1, cpDNA trnL and cpDNA rps16 from the Indian subcontinent
(Indian Academy of Sciences, 2019)Ficus benghalensis Linnaeus (Moraceae) is the national tree of India and is well known for its pharmacolo-gical properties. The present study was aimed to determine the genetic diversity of F. benghalensis from the Indian ... -
Monetary response to global financial crisis in india econometrics analysis
(Central University of Punjab, 2014)This study has examined India's monetary policy response to global financial crisis by applying Taylor's rule with the aid of Autoregressive Distributed Lag model. It also investigates monetary policy response during pre ... -
Monitoring of mahatama gandhi national rural employment guarantee scheme in kulgam district of jammu and kashmir
(Central University of Punjab, 2013)The study entitled "Monitoring of Mahatma Gandhi National Rural Employment Guarantee Scheme in Kulgam District of Jammu and Kashmir" is an attempt to assess the implementation of this Scheme. It brings out the violations ... -
Monitoring of mahatma gandhi national rural employment gurantee scheme in bathinda district of punjab
(Central University of Punjab, 2014)The Mahatama Gandhi National Rural Employment Guarantee Act of Government of India was introduced primarily to enhance the livelihood of households by providing 100 days employment to the adult members. It provides ... -
Monkeypox infection: The past, present, and future
(Elsevier B.V., 2022-10-29)Monkeypox is a zoonotic illness caused by the monkeypox virus (MPXV) that has a similar etiology to smallpox. The first case of monkeypox was reported in Western and Central Africa in 1971, and in 2003, there was an outbreak ... -
Monkeypox Viral Transmission Dynamics And Fractional-Order Modeling With Vaccination Intervention
(World Scientific, 2023-03-20)A current outbreak of the monkeypox viral infection, which started in Nigeria, has spread to other areas of the globe. This affects over 28 nations, including the United Kingdom and the United States. The monkeypox virus ...