Browsing by Author "Jain, A."
Now showing items 1-6 of 6
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Cancer Susceptibility Candidate 9 (CASC9): A Novel Targetable Long Noncoding RNA in Cancer Treatment
Sharma, U; Barwal, T.S; Acharya, V; Tamang, S; Vasquez, K.M; Jain, A. (Neoplasia Press, Inc., 2020)Based on epidemiological data provided by the World Health Organization (2018), cancer is the second most prevalent cause of death worldwide. Several factors are thought to contribute to the high mortality rate in cancer ... -
Circulating microRNA-590-5p functions as a liquid biopsy marker in non-small cell lung cancer
Khandelwal, A; Seam, R.K; Gupta, M; Rana, M.K; Prakash, H; Vasquez, K.M; Jain, A. (Blackwell Publishing Ltd, 2020)Despite the availability of various diagnostic procedures, a tissue biopsy is still indispensable for the routine diagnosis of lung cancer. However, inaccurate diagnoses can occur, leading to inefficient cancer management. ... -
The emerging role of long non-coding RNA in gallbladder cancer pathogenesis
Khandelwal, Akanksha; Malhotra, Akshay; Jain, Manju; Vasquez, Karen M.; Jain, Aklank; Khandelwal, A.; Malhotra, A.; Jain, M.; Vasquez, K.M.; Jain, A. (Elsevier B.V., 2017)Gallbladder cancer (GBC) is the most common and aggressive form of biliary tract carcinoma with an alarmingly low 5-year survival rate. Despite its high mortality rate, the underlying mechanisms of GBC pathogenesis are not ... -
The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer
Malhotra, Akshay; Jain, Manju; Prakash, Hridayesh; Vasquez, Karen M.; Jain, Aklank; Malhotra, A.; Jain, M.; Prakash, H.; Vasquez, K.M.; Jain, A. (Impact Journals LLC, 2017)Chemoresistance is one of the major hurdles in the treatment of breast cancer, which limits the effect of both targeted and conventional therapies in clinical settings. Therefore, understanding the mechanisms underpinning ... -
SNHG12: An LncRNA as a Potential Therapeutic Target and Biomarker for Human Cancer
Tamang, S; Acharya, V; Roy, D; Sharma, R; Aryaa, A; Sharma, U; Khandelwal, A; Prakash, H; Vasquez, K.M; Jain, A. (Frontiers Media S.A., 2019)Limitations in current diagnostic procedures warrant identification of new methodologies to improve diagnoses of cancer patients. In this context, long non-coding RNAs (lncRNAs) have emerged as stable biomarkers which are ... -
Stabilization of miRNAs in esophageal cancer contributes to radioresistance and limits efficacy of therapy.
Malhotra, A; Sharma, U; Puhan, S; Chandra, Bandari N; Kharb, A; Arifa, PP; Thakur, L; Prakash, H; Vasquez, KM; Jain, A. (Elsevier, 2019)The five-year survival rate of esophageal cancer patients is less than 20%. This may be due to increased resistance (acquired or intrinsic) of tumor cells to chemo/radiotherapies, often caused by aberrant cell cycle, ...