Browsing by Subject "Angiogenesis"
Now showing items 1-5 of 5
-
Differential molecular mechanistic behavior of HDACs in cancer progression
(Springer, 2022-08-16)Genetic aberration including mutation in oncogenes and tumor suppressor genes transforms normal cells into tumor cells. Epigenetic modifications work concertedly with genetic factors in controlling cancer development. ... -
Low dose radiation primed iNOS + M1macrophages modulate angiogenic programming of tumor derived endothelium.
(PLOS, 2018)Solid tumors are covered by stroma, which is hypoxic in nature and composed of various non‐malignant components such as endothelial cells, fibroblasts, and pericytes that support tumor growth. Tumor stroma represents a ... -
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis
(Springer Science and Business Media Deutschland GmbH, 2022-11-28)ROS include hydroxyl radicals (HO.), superoxide (O2.), and hydrogen peroxide (H2O2). ROS are typically produced under physiological conditions and play crucial roles in living organisms. It is known that ROS, which are ... -
Role of reactive oxygen species in cancer progression: Molecular mechanisms and recent advancements
(MDPI AG, 2019)Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration ... -
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(Springer Science and Business Media B.V., 2022-04-26)As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ...