Now showing items 1-3 of 3

    • Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis 

      Eaves-Pyles, Tonyia; Patel, Jignesh; Arigi, Emma; Cong, Yingzi; Cao, Anthony; Garg, Nisha; Dhiman, Monisha; Pyles, Richard B.; Arulanandam, Bernard; Miller, Aaron L.; Popov, Vsevolod L.; Soong, Lynn; Carlsen, Eric D.; Coletta, Ciro; Szabo, Csaba; Almeida, Igor C. (2013)
      Cystatin 9 (CST9) is a member of the type 2 cysteine protease inhibitor family, which has been shown to have immunomodulatory effects that restrain inflammation, but its functions against bacterial infections are unknown. ...
    • miR-30c and miR-181a synergistically modulate p53?p21 pathway in diabetes induced cardiac hypertrophy 

      Raut, Satish K.; Singh, Gurinder B.; Rastogi, Bhawna; Saikia, Uma Nahar; Mittal, Anupam; Dogra, Nilambra; Singh, Sandeep; Prasad, Rishikesh; Khullar, Madhu (Springer New York LLC, 2016)
      p53?p21 pathway mediates cardiomyocyte hypertrophy and apoptosis and is upregulated in diabetic cardiomyopathy (DbCM). We investigated role of microRNAs in regulating p53?p21 pathway in high glucose (HG)-induced cardiomyocyte ...
    • Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors 

      Jongbloets, Bart C.; Lemstra, Suzanne; Schellino, Roberta; Broekhoven, Mark H.; Parkash, Jyoti; Hellemons, Anita J.C.G.M.; Mao, Tianyi; Giocobini, Paolo; Praag, Henriette Van; Marchis, Silvia De; Ramakers, Geert M.J.; Pasterkamp, R. Jeroen; Jongbloets, B.C.; Lemstra, S.; Schellino, R.; Broekhoven, M.H.; Parkash, J.; Hellemons, A.J.C.G.M.; Mao, T.; Giacobini, P.; Van Praag, H.; De Marchis, S.; Ramakers, G.M.J.; Pasterkamp, R.J. (Nature Publishing Group, 2017)
      The guidance protein Semaphorin7A (Sema7A) is required for the proper development of the immune and nervous systems. Despite strong expression in the mature brain, the role of Sema7A in the adult remains poorly defined. ...