Browsing by Subject "Cell Cycle"
Now showing items 1-3 of 3
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ASSOCIATION OF OXIDATIVE STRESS WITH CYP1A2, CYP3A4, CYP2B6 AND PON1 GENETIC POLYMORPHISM IN AGRICULTURAL COMMUNITY OF BATHINDA
(Central University of Punjab, 2018)The aim of present study is to evaluate the association of oxidative stress with CYP1A2, CYP3A4, CYP2B6 and PON1 genetic variation in the pesticide exposed (occupationally) population. The present study demonstrated that ... -
Human apurinic/apyrimidinic endonuclease (APE1) is acetylated at DNA damage sites in chromatin, and acetylation modulates its DNA repair activity
(American Society for Microbiology, 2016)Apurinic/apyrimidinic (AP) sites, the most frequently formed DNA lesions in the genome, inhibit transcription and block replication. The primary enzyme that repairs AP sites in mammalian cells is the AP endonuclease (APE1), ... -
Pesticide Induced Cytotoxicity Analysis in Human Cells
(Krishi Sanskriti Publications, 2017)The aim of our work was to evaluate the effect of pesticides on cell survival, oxidative stress mechanism in hPBMC (human Peripheral Blood Mononucleated Cells) and lung cancer cells (A549 cell line). Cells were exposed to ...