Browsing by Subject "Drug Design"
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A Perspective on Monoamine Oxidase Enzyme as Drug Target: Challenges and Opportunities
(2017)The monoamine oxidase (MAO) enzyme is responsible for the deamination of monoamine neurotransmitters and regulates their concentration in the central and peripheral nervous systems. Imbalance in the concentration of ... -
Toxicophore exploration as a screening technology for drug design and discovery: techniques, scope and limitations
(Springer Verlag, 2016)Toxicity is a common drawback of newly designed chemotherapeutic agents. With the exception of pharmacophore-induced toxicity (lack of selectivity at higher concentrations of a drug), the toxicity due to chemotherapeutic ...