Now showing items 1-5 of 5

    • Drug Discovery and Development: From Targets and Molecules to Medicines 

      Poduri, Ramarao (Springer Singapore, 2021-02-18)
      This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug ...
    • Exploration of Pd-catalysed four-component tandem reaction for one-pot assembly of pyrazolo[1,5-c]quinazolines as potential EGFR inhibitors 

      Ansari, A.J; Joshi, G; Yadav, U.P; Maurya, A.K; Agnihotri, V.K; Kalra, S; Kumar, R; Singh, S; Sawant, D.M. (Academic Press Inc., 2019)
      A series of pyrazolo[1,5-c]quinazolines as EGFR inhibitors was designed and synthesized by highly efficient and novel multicomponent route involving Pd-catalyzed tandem one-pot four-component reaction. The reaction proceeds ...
    • An Overview on Biological Activities of 1,2,3-Triazole Derivatives 

      Kabi, Arup K.; Sravani, Sattu; Gujjarappa, Raghuram; Garg, Aakriti; Vodnala, Nagaraju; Tyagi, Ujjawal; Kaldhi, Dhananjaya; Singh, Virender; Gupta, Sreya; Malakar, Chandi C. (Springer Nature, 2022-03-07)
      Among the nitrogen-embedded heterocycles, 1,2,3-triazoles derivatives are widely explored and earned considerable attraction in pharmaceutical industry and academics. 1,2,3-Triazoles have attracted significant consideration ...
    • An Overview on Biological Activity of Benzimidazole Derivatives 

      Kabi, Arup K.; Sravani, Sattu; Gujjarappa, Raghuram; Garg, Aakriti; Vodnala, Nagaraju; Tyagi, Ujjawal; Kaldhi, Dhananjaya; Singh, Virender; Gupta, Sreya; Malakar, Chandi C. (Springer Nature, 2022-03-07)
      Benzimidazole moiety plays a key role in variety of heterocyclic scaffolds which derive the biological functioning of essential molecules. Because of the skeletal resemblance with the naturally appearing nucleotides, ...
    • An Overview on Biological Evaluation of Tetrazole Derivatives 

      Kabi, Arup K.; Sravani, Sattu; Gujjarappa, Raghuram; Garg, Aakriti; Vodnala, Nagaraju; Tyagi, Ujjawal; Kaldhi, Dhananjaya; Velayutham, Ravichandiran; Singh, Virender; Gupta, Sreya; Malakar, Chandi C. (Springer Nature, 2022-03-07)
      Tetrazoles are distinguished by a five-membered, doubly unsaturated ring which consists of four nitrogen and one carbon atom with a molecular formula CN4H2, which have a wide range of medicinal activity and potential role ...