Now showing items 1-2 of 2

    • Alterations in cellular metabolisms after Imatinib therapy: a review 

      Kumar, Veerandra; Singh, Priyanka; Gupta, Sonu Kumar; Ali, Villayat; Jyotirmayee; Verma, Malkhey (Springer, 2022-05-16)
      Chronic myeloid leukemia (CML) is characterized by the possession of the Philadelphia chromosome, which contains the Bcr-Abl oncogene that codes for the oncoprotein BCR-ABL. Through glucose metabolism, glycolysis, and the ...
    • Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase 

      Dong, Shengli; Baranwal, Somesh; Garcia, Anapatricia; Serrano-Gomez, Silvia; Eastlack, Steven; Iwakuma, Tomoo; Mercante, Donald; Mauvais-Jarvis, Franck; Alahari, Suresh K.; Dong, S.; Baranwal, S.; Garcia, A.; Serrano-Gomez, S.J.; Eastlack, S.; Iwakuma, T.; Mercante, D.; Mauvais-Jarvis, F.; Alahari, S.K. (American Society for Biochemistry and Molecular Biology Inc., 2017)
      Nischarin (Nisch) is a key protein functioning as a molecular scaffold and thereby hosting interactions with several protein partners. To explore the physiological importance of Nisch, here we generated Nisch loss-of-function ...