Browsing by Subject "Huntington�s disease"
Now showing items 1-4 of 4
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Animal models of Huntington�s disease and their applicability to novel drug discovery and development
(Taylor and Francis Ltd., 2023-04-12)Introduction: Huntington�s disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the CAG trinucleotide repeat in huntingtin (Htt) gene. The discovery of the HD-causing gene prompted the creation ... -
Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats
(Springer, 2022-11-17)Striatal neurotoxicity is the pathological hallmark for a heterogeneous group of movement disorders like Tardive dyskinesia (TD) and Huntington�s disease (HD). Both diseases are characterized by progressive impairment in ... -
GSK-3?-mediated regulation of Nrf2/HO-1 signaling as a new therapeutic approach in the treatment of movement disorders
(Springer Science and Business Media Deutschland GmbH, 2022-07-27)Movement disorders are neurological conditions characterized by involuntary motor movements, such as dystonia, ataxia, chorea myoclonus, tremors, Huntington�s disease (HD), and Parkinson�s disease (PD). It is classified ... -
Neuroprotection through G-CSF: recent advances and future viewpoints
(Springer Science and Business Media Deutschland GmbH, 2021-01-02)Granulocyte-colony stimulating factor (G-CSF), a member of the cytokine family of hematopoietic growth factors, is 19.6�kDa glycoprotein which is responsible for the proliferation, maturation, differentiation, and survival ...