Browsing by Subject "Metformin"
Now showing items 1-6 of 6
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ANALYSIS OF MICRORNA SIGNATURES AS BIOMARKER TO INVESTIGATE INTERLINK BETWEEN TYPE 2 DIABETES AND BREAST CANCER
(Central University of Punjab, 2018)Type 2 diabetes and breast cancer are two heterogeneous, multifactorial, chronic health problems involving several overlapping risk factors. Studies have suggested that type 2 diabetes is associated with 10-20% excessive ... -
Effect of metform on insuln mediated proliferation of lung cancer cell lines
(Central University of Punjab, 2012)Background: The incidence of cancer in diabetes mellitus (DM) patients is a matter of concern. Lung cancer is the most commonly diagnosed cancer and leading cause of death in males. Smoking is the main risk factor contributing ... -
Host-Guest Interaction of calix[4]arene derivatives with MetforminAC
(Central University of Punjab, 2018)Calix[4]arene was lower rim functionalized to furnish receptor 2-3 and 4-6, containing propyl and cyanomethoxy moieties, respectively. The receptors were characterized by FTIR, 1H and EI-MS. UV-visible studies were performed ... -
INFLUENCE OF INSULIN AND METFORMIN ON PROSTATE CANCER
(Nova Science Publishers, 2017)Dietary habit and hormonal factor play a significant role in prostate cancer deregulation in addition to genetic and environmental factor. Nonandrogenic growth factor like insulin and insulin growth factor are influences ... -
Metformin inhibits human breast cancer cell growth by promoting apoptosis via a ROS-independent pathway involving mitochondrial dysfunction: pivotal role of superoxide dismutase (SOD)
(Springer, 2018)Purpose Despite a growing body of evidence indicating a potential efficacy of the anti-diabetic metformin as anti-cancer agent, the exact mechanism underlying this efficacy has remained largely unknown. Here, we aimed at ... -
To Study the Dose and Time Dependent Effect of Human Insulin and Metformin on the Growth of Breast Cancer Cells
(Central University of Punjab, 2012)Cancer and diabetes, both are leading causes of mortality globally. Both the diseases are multifactorial and share number of common risk factors. Hyperglycemia and hyperinsulinemia which are the characteristic features ...