Now showing items 1-3 of 3

    • miRNAs as Therapeutic Target in Obesity and Cancer 

      Prajapati, Kumari Sunita; Shuaib, Mohd; Kushwaha, Prem Prakash; Singh, Atul Kumar; Sharma, Rahul; Kumar, Shashank (Springer Singapore, 2021-07-18)
      MicroRNAs are small non-coding RNAs that regulate the expression of many genes. Alteration of microRNA expressions is associated with the occurrence of diseases including cancer, obesity, and obesity-related cancer. miRNAs ...
    • Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection 

      Tuli, Hardeep Singh; Garg, Vivek Kumar; Bhushan, Sakshi; Uttam, Vivek; Sharma, Uttam; Jain, Aklank; Sak, Katrin; Yadav, Vikas; Lorenzo, Jose M.; Dhama, Kuldeep; Behl, Tapan; Sethi, Gautam (Neoplasia Press, Inc., 2022-12-05)
      Cancer prevalence and its rate of incidence are constantly rising since the past few decades. Owing to the toxicity of present-day antineoplastic drugs, it is imperative to explore safer and more effective molecules to ...
    • Stabilization of miRNAs in esophageal cancer contributes to radioresistance and limits efficacy of therapy. 

      Malhotra, A; Sharma, U; Puhan, S; Chandra, Bandari N; Kharb, A; Arifa, PP; Thakur, L; Prakash, H; Vasquez, KM; Jain, A. (Elsevier, 2019)
      The five-year survival rate of esophageal cancer patients is less than 20%. This may be due to increased resistance (acquired or intrinsic) of tumor cells to chemo/radiotherapies, often caused by aberrant cell cycle, ...