Now showing items 1-5 of 5

    • Drug Discovery and Development: From Targets and Molecules to Medicines 

      Poduri, Ramarao (Springer Singapore, 2021-02-18)
      This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug ...
    • FDA approved fused pyrimidine-based drugs 

      Thakur, Shikha; Ansari, Arshad J.; Joshi, Gaurav (Elsevier, 2022-10-14)
      The present chapter is a compilation and analysis of USFDA approved small drug candidates about fused pyrimidine pharmacophore. Out of 63 drugs approved so far, nearly 38% of drugs are approved for chemotherapeutic treatment ...
    • Genetic signatures in ischemic stroke: Focus on aspirin resistance 

      Vasudeva, Kanika; Chaurasia, Pratibha; Singh, Sulena; Munshi, Anjana (Bentham Science Publishers B.V., 2017)
      Background and Objective: Stroke is one of the leading causes of death. There has been compelling evidence that stroke has a genetic component. Genetic variants not only influence susceptibility to stroke but have also ...
    • Pharmacogenomics of GLP-1 receptor agonists: Focus on pharmacological profile 

      Jakhar, Kalpna; Vaishnavi, Swetha; Kaur, Prabhsimran; Singh, Paramdeep; Munshi, Anjana (Elsevier B.V., 2022-10-28)
      Type 2 Diabetes mellitus (T2DM) is a multifactorial metabolic disorder also known as a silent killer disease. Macrovascular and microvascular complications associated with diabetes worsen the condition leading to higher ...
    • �The pharmacological profile of SGLT2 inhibitors: Focus on mechanistic aspects and pharmacogenomics� 

      Kaur, Prabhsimran; Behera, Bidwan Sekhar; Singh, Sandeep; Munshi, Anjana (Elsevier B.V., 2021-05-11)
      Diabetes, characterized by high glucose levels, has been listed to be one of the world's major causes of death. Around 1.6 million deaths are attributed to this disease each year. Persistent hyperglycemic conditions in ...