Now showing items 1-3 of 3

    • A comprehensive overview of CRISPR/Cas 9 technology and application thereof in drug discovery 

      Khurana, Amit; Sayed, Nilofer; Singh, Vishakha; Khurana, Isha; Allawadhi, Prince; Rawat, Pushkar Singh; Navik, Umashanker; Pasumarthi, Sravan Kumar; Bharani, Kala Kumar; Weiskirchen, Ralf (John Wiley and Sons Inc, 2022-09-21)
      Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Cas technology possesses revolutionary potential to positively affect various domains of drug discovery. It has initiated a rise in the area of genetic ...
    • Missing link between microRNA and prostate cancer 

      Gill, Balraj Singh; Alex, Jimi Marin; Navgeet; Kumar, Sanjeev; Gill, B.S.; Alex, J.M.; Navgeet, Kumar, S. (Springer Netherlands, 2016)
      MicroRNAs are the non-coding RNAs which regulate endogenous gene expression in animal and plant cells. Alterations in the level of micro-ribonucleic acids (miRNAs) involving the deletions, overexpression, mutations, ...
    • A short review on the implications of base excision repair pathway for neurons: Relevance to neurodegenerative diseases 

      Mantha, Anil K.; Sarkar, Bibekananda; Tell, Gianluca (Elsevier, 2014)
      Oxidative DNA damage results from the attack by reactive oxygen and nitrogen species (ROS/RNS) on human genome. This includes base modifications such as oxidized bases, abasic (AP) sites, and single-strand breaks (SSBs), ...