Browsing by Subject "Sirtuin 1"
Now showing items 1-3 of 3
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Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair
(Impact Journals LLC, 2016)Apurinic/apyrimidinic (AP) sites are frequently generated in the genome by spontaneous depurination/depyrimidination or after removal of oxidized/modified bases by DNA glycosylases during the base excision repair (BER) ... -
L-Methionine supplementation attenuates high-fat fructose diet-induced non-alcoholic steatohepatitis by modulating lipid metabolism, fibrosis, and inflammation in rats
(Royal Society of Chemistry, 2022-03-31)Recently, the protective effects of a methionine-rich diet on hepatic oxidative stress and fibrosis have been suggested but not adequately studied. We, therefore, hypothesized that l-methionine supplementation would ... -
The mitochondrial unfolded protein response: Role in cellular homeostasis and disease
(Bentham Science Publishers B.V., 2017)Mitochondria are the sole semiautonomous organelles of the human cell and play a very important role in not only energy production but also in apoptosis, metabolism and cell signaling. They are also known to be major ...