Now showing items 1-10 of 10

    • Biomedical applications of L-alanine produced by Pediococcus acidilactici BD16 (alaD +) 

      Sharma, Anshula; Mehta, Vikrant; Rani, Suman; Noda, Masafumi; Sugiyama, Masanori; Chander, Harish; Kaur, Baljinder (Springer Science and Business Media Deutschland GmbH, 2022-01-28)
      Abstract: L-alanine possesses extensive physiological functionality and tremendous pharmacological significance, therefore could be considered as potential ingredient for food, pharmaceutical, and personal care products. ...
    • Components of IGF-axis in growth disorders: a systematic review and patent landscape report 

      Singh, Amit; Pajni, Ketan; Panigrahi, Inusha; Dhoat, Navdeep; Senapati, Sabyasachi; Khetarpal, Preeti (Springer, 2022-05-06)
      Purpose: In this review, epi/genetic mutations of IGF-axis components associated with growth disorders have been summarized alongwith assessment of relevant diagnostic and therapeutic technology through patent literature. ...
    • Diagnostic and therapeutic approaches for endometriosis: a patent landscape 

      Singh, Maninder; Jassal, Reena; Khetarpal, Preeti (Springer Science and Business Media Deutschland GmbH, 2023-08-25)
      Objective: The aim of this review is to analyze the patent filings and to systematize the main technological trends in patent protection for the diagnosis and therapeutics for endometriosis. Patent literature has also been ...
    • Evolving strategies and application of proteins and peptide therapeutics in cancer treatment 

      Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Gopalakrishnan, Abilash Valsala; Bradu, Pragya; Biswas, Antara; Ganesan, Raja; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; El Allali, Achraf; Alsamman, Alsamman M.; Zayed, Hatem; George Priya Doss, C. (Elsevier Masson s.r.l., 2023-05-05)
      Several proteins and peptides have therapeutic potential and can be used for cancer therapy. By binding to cell surface receptors and other indicators uniquely linked with or overexpressed on tumors compared to healthy ...
    • The journey of noncoding RNA from bench to clinic 

      Chhabra, Ravindresh (Elsevier, 2021-01-30)
      The discovery of noncoding RNA (ncRNA) in the 90s completely changed our understanding of gene regulation. The ncRNAs specialize in regulating the gene expression, which enables them to induce a remarkable change in cellular ...
    • Legume lectins: Potential use as a diagnostics and therapeutics against the cancer 

      Gautam A.K.; Sharma D.; Sharma J.; Saini K.C. (Elsevier B.V., 2020)
      Legume lectins are carbohydrate-binding protein and widely distributed in a variety of species of leguminous plants and have drawn increased attention toward cancer. Nowadays, the lectins have been studied for the screening ...
    • Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer�s disease 

      Dhapola, Rishika; Hota, Subhendu Shekhar; Sarma, Phulen; Bhattacharyya, Anusuya; Medhi, Bikash; Reddy, Dibbanti HariKrishna (Springer Science and Business Media Deutschland GmbH, 2021-11-23)
      Alzheimer�s disease (AD) is a major contributor of dementia leading to the degeneration of neurons in the brain with major symptoms like loss of memory and learning. Many evidences suggest the involvement of neuroinflammation ...
    • Role of p53 gene in breast cancer: Focus on mutation spectrum and therapeutic strategies 

      Kaur, Raman Preet; Vasudeva, Kanika; Kumar, Roshan; Munshi, Anjana (Bentham Science Publishers B.V., 2018)
      TP53 is a tumor suppressor gene which is commonly mutated in various cancers including breast cancer. Alterations in the gene lead to an altered expression of various genes that are directly or indirectly under the ...
    • STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation 

      Tuli, Hardeep Singh; Sak, Katrin; Iqubal, Ashif; Garg, Vivek Kumar; Varol, Mehmet; Sharma, Uttam; Chauhan, Abhishek; Yerer, Mukerrem Betul; Dhama, Kuldeep; Jain, Manju; Jain, Aklank (Springer Science and Business Media B.V., 2022-04-26)
      As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ...
    • Type 2 Diabetes (T2DM) and Parkinson�s Disease (PD): a Mechanistic Approach 

      Sabari, S. Sri; Balasubramani, Kiruthika; Iyer, Mahalaxmi; Sureshbabu, Harysh Winster; Venkatesan, Dhivya; Gopalakrishnan, Abilash Valsala; Narayanaswamy, Arul; Senthil Kumar, Nachimuthu; Vellingiri, Balachandar (Springer, 2023-04-28)
      Growing evidence suggest that there is a connection between Parkinson�s disease (PD) and insulin dysregulation in the brain, whilst the connection between PD and type 2 diabetes mellitus (T2DM) is still up for debate. ...