Browsing by Subject "cancer"
Now showing items 1-10 of 17
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Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach
(John Wiley and Sons Inc, 2023-10-04)mRNA vaccines have long been recognized for their ability to induce robust immune responses. The discovery that mRNA vaccines may also contribute to antitumor immunity has made them a promising therapeutic approach against ... -
Anticancer activity of dihydropyrazolo[1,5-c]quinazolines against rat C6 glioma cells via inhibition of topoisomerase II.
(Wiley, 2018)The design and synthesis of dihydropyrazolo[1,5‐c]quinazolines (1a–h) as human topoisomerase II (TopoII) catalytic inhibitors are reported. The compounds were investigated for their antiproliferative activity against the ... -
Circulating miR-320a Acts as a Tumor Suppressor and Prognostic Factor in Non-small Cell Lung Cancer
(Frontiers Media S.A., 2021-03-23)Dysregulated expression profiles of microRNAs (miRNAs) have been observed in several types of cancer, including non-small cell lung cancer (NSCLC); however, the diagnostic and prognostic potential of circulating miRNAs in ... -
Discovery of Natural Anti-Apoptotic Protein Inhibitor Using Molecular Docking and MM-GBSA Approach: An Anticancer Intervention
(AMG Transcend Association, 2022-12-27)Apoptosis is a programmed molecular phenomenon in normal cells, and "evading apoptosis" is a hallmark of cancer. Overexpression of anti-apoptotic BCL-2 promotes cancer cell survival, leading to tumor formation, its maintenance ... -
DNA barcode-based identification and comparative anti-cancer effects of different species of brown seaweed Sargassum C. Agardh of Indian coasts
(Central University of Punjab, 2018)Sargassum C. Agardh is a ubiquitous, multicellular brown seaweed that represents the most species-rich genus of the brown algal order Fucales, with more than 500 species reported worldwide. The present study aimed to ... -
DNA barcoding and phylogeny based comparative evaluation of anti-cancer properties of Caulerpa (J V Lamouroux) spp. from Indian coasts
(Central University of Punjab, 2019)A total of 15 Caulerpa samples were collected from Indian coasts and identified based on morphological and molecular data inferred from ITS, 18S, tufA and rbcL. Seven different species viz. C. scalpelliformis, C. racemosa, ... -
Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis
(Frontiers Media S.A., 2019)Tumor metastasis is a sequential event accounting for numerous cancer-related fatalities worldwide. The process of metastasis serially involves invasion, intravasation, extravasation, and tumor growth at the secondary site. ... -
Exploration of Pharmacological Potential of Alpinetin
(Bentham Science Publishers, 2022-05-13)Secondary metabolites found in plants are a natural source of bioactive chemicals. These secondary metabolites are vital for the survival of plants and have a number of medicinal properties, which can be utilised to treat ... -
Impact of noncoding RNAs on cancer directed immune therapies: Now then and forever
(John Wiley and Sons Inc, 2022-04-30)Accumulating evidence demonstrates that the host genome's epigenetic modifications are essential for living organisms to adapt to extreme conditions. DNA methylation, covalent modifications of histone and interassociation ... -
An Insight to Heat Shock Protein 90: A Remedy for Multiple Problems
(Bentham Science Publishers, 2022-08-30)Heat shock protein 90 (Hsp90) is a chaperone protein that prevents many other proteins from aggre-gating by folding them in a certain way. Hsp90 consists of three structural domains: N-terminal, middle and C-terminal ...