Browsing by Subject "cell migration"
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Mechanisms of tubulin binding ligands to target cancer cells: Updates on their therapeutic potential and clinical trials
(Bentham Science Publishers B.V., 2017)Background: A number of chemically diverse substances bind to the tubulin and inhibit cell proliferation by disrupting microtubule dynamics. There are four binding sites for the ligands binding to the tubulin; taxane/epothilone ... -
Screening of multi-targeted natural compounds for receptor tyrosine kinases inhibitors and biological evaluation on cancer cell lines, in silico and in vitro
(Humana Press Inc., 2015)Receptors for growth factors encompass within the superfamily of receptor tyrosine kinases and are known to regulate numerous biological processes including cellular growth, proliferation, metabolism, survival, cell ...