Browsing by Subject "indole"
Now showing items 1-4 of 4
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Design, Synthesis and Evaluation of Indole Based Compounds as Putative Anticancer Agents
(Central University of Punjab, 2018)In the course of efforts to develop new chemotherapeutic agent for targeting breast cancer, indole-benzimidazole, indole-xanthendione, indole-chromene carbonitrile and indole-dihydropyridine derivatives were computationally ... -
In Silico Studies of Indole Derivatives as Antibacterial Agents
(Korean Pharmacopuncture Institute, 2023-06-30)Objectives: Molecular docking and QSAR studies of indole derivatives as antibacterial agents. Methods: In this study, we used a multiple linear regressions (MLR) approach to construct a 2D quantitative structure activity ... -
A Minireview on the Scope of Cadogan Cyclization Reactions Leading to Diverse Azaheterocycles
(John Wiley and Sons Inc, 2022-04-01)From the last two decades, Cadogan cyclization reaction is considered as one of the best routes for the preparation of various azaheterocycles comprising carbazoles, indoles, coumarins, carbolines, pyrazoloquinoxalines, ... -
Molecular docking, 3D-QSAR and simulation studies for identifying pharmacophoric features of indole derivatives as 17?-hydroxysteroid dehydrogenase type 5 (17?-HSD5) inhibitors
(Taylor and Francis Ltd., 2023-02-06)Excess of androgens leads to various diseases such as Poly-Cystic Ovarian Syndrome, Prostate Cancer, Hirsutism, Obesity and Acne. 17?-Hydroxysteroid Dehydrogenase type 5 (17?-HSD5) converts androstenedione into testosterone ...