Browsing by Subject "multi-target directed ligands"
Now showing items 1-3 of 3
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Design Strategies, Chemistry and Therapeutic Insights of Multi-target Directed Ligands as Antidepressant Agents
(Bentham Science Publishers, 2021-11-03)Depression is one of the major disorders of the central nervous system worldwide and causes disability and functional impairment. According to the World Health Organization, around 265 million people worldwide are affected ... -
Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer�s Disease
(Bentham Science Publishers, 2021-05-12)Alzheimer�s disease (AD) is a complex neurological disorder and multiple pathological factors are believed to be involved in the genesis and progression of the disease. A number of hypothesis including Acetylcholinesterase, ... -
Virtual screening and molecular dynamics simulation approach for the identification of potential multi-target directed ligands for the treatment of Alzheimer�s disease
(Taylor and Francis Ltd., 2023-04-28)Alzheimer�s disease (AD) is a multifactorial neurological disorder characterized by memory loss and cognitive impairment. The currently available single-targeting drugs have miserably failed in the treatment of AD, and ...