Browsing by Subject "neurodegeneration"
Now showing items 1-4 of 4
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Animal models of Huntington�s disease and their applicability to novel drug discovery and development
(Taylor and Francis Ltd., 2023-04-12)Introduction: Huntington�s disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the CAG trinucleotide repeat in huntingtin (Htt) gene. The discovery of the HD-causing gene prompted the creation ... -
Calcium channelopathies in neurodegenerative disorder: an untold story of RyR and SERCA
(Taylor and Francis Ltd., 2023-11-16)Introduction: Recent neuroscience breakthroughs have shed light on the sophisticated relationship between calcium channelopathies and movement disorders, exposing a previously undiscovered tale focusing on the Ryanodine ... -
Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson�s Disease: An In Silico and In Vivo Study
(Frontiers Media S.A., 2021-03-16)Ethnopharmacological Relevance: Parkinson�s disease (PD) is characterized by progressive death of dopaminergic neurons. The presently used medicines only tackle the symptoms of PD, but none makes a dent on the processes ... -
Targeting mitochondria in the regulation of neurodegenerative diseases: A comprehensive review
(John Wiley and Sons Inc, 2022-07-20)Mitochondria are one of the essential cellular organelles. Apart from being considered as the powerhouse of the cell, mitochondria have been widely known to regulate redox reaction, inflammation, cell survival, cell death, ...