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Genetic determinants in ischaemic stroke subtypes: Seven year findings and a review

dc.contributor.authorMunshi, Anjana
dc.contributor.authorDas,Satrupa.
dc.contributor.authorKaul, Subhash
dc.date.accessioned2018-07-10T07:30:30Z
dc.date.available2018-07-10T07:30:30Z
dc.date.issued2015
dc.identifier.citationMunshi, A., Das, S., & Kaul, S. (2015). Genetic determinants in ischaemic stroke subtypes: Seven year findings and a review. Gene, 555(2), 250-259. doi: 10.1016/j.gene.2014.11.015en_US
dc.identifier.issn3781119
dc.identifier.urihttp://kr.cup.edu.in/handle/32116/1050
dc.description.abstractStroke is a global health problem and a leading cause of disability worldwide. There have been numerable studies undertaking research on different aspects of ischaemic stroke employing various epidemiological, clinical and molecular parameters. Nevertheless ischaemic stroke being a complex disorder with different subtypes demands equal attention towards its subtypes too. Since there has been enough evidence that disposition to certain subtype is genetically determined and there is a distinct mechanism that influences its development, association studies should focus on subtypes simultaneously while studying specific genes. Data from such studies will thus provide better and intricate findings with regard to heterogenous ischaemic stroke. In the present review we discuss the genes studied by our group over a period of seven years in association with stroke subtypes in a South Indian population and correlate the findings with similar genetic studies from other populations so as to provide an overview of various genes involved in the pathogenesis of ischaemic stroke subtypes. ? 2014 Elsevier B.V.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectadult; Article; brain ischemia; DNA polymorphism; female; genetic analysis; genetic association; human; Indian; major clinical study; male; pathogenesis; aged; cerebrovascular accident; computer assisted tomography; DNA sequence; ethnology; genetic polymorphism; genetic predisposition; genetics; genotype; geography; India; ischemia; middle aged; neurology; nuclear magnetic resonance imaging; risk factor; Aged; Female; Genetic Predisposition to Disease; Genotype; Geography; Humans; India; Ischemien_US
dc.titleGenetic determinants in ischaemic stroke subtypes: Seven year findings and a reviewen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.gene.2014.11.015
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0378111914012761?via%3Dihub
dc.title.journalGene


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