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Indian Herbs and their Therapeutic Potential against Alzheimer’s Disease and other Neurological Disorders
(Wiley, 2017)
Many present-day diseases are caused by disruption of the delicate balance between the reactive oxygen/nitrogen species (ROS/RNS) produced by oxidants and their scavenging by the antioxidants in the body. Chief among them ...
Understanding human thiol dioxygenase enzymes: structure to function and biology to pathology
(Wiley, 2017)
Amino acid metabolism is a significant metabolic activity in humans, especially of sulphur-containing amino acids, methionine and cysteine (Cys). Cys is cytotoxic and neurotoxic in nature; hence, mammalian cells maintain ...
Curcumin revitalizes Amyloid beta (25–35)-induced and organophosphate pesticides pestered neurotoxicity in SH-SY5Y and IMR-32 cells via activation of APE1 and Nrf2
(Springer, 2017)
Amyloid beta (Aβ) peptide deposition is the primary cause of neurodegeneration in Alzheimer’s disease (AD) pathogenesis. Several reports point towards the role of pesticides in the AD pathogenesis, especially organophosphate ...