Department of Zoology: Recent submissions
Now showing items 1-20 of 185
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Circulating long non-coding RNA EWSAT1 acts as a liquid biopsy marker for esophageal squamous cell carcinoma: A pilot study
(KeAi Communications Co., 2023-10-28)The widespread public health problem of esophageal squamous cell carcinoma (ESCC) is the cause of an increasing number of deaths each year due to delayed diagnosis. Therefore, we require specific and sensitive new biomarkers ... -
Implicative role of cytokines in neuroinflammation mediated AD and associated signaling pathways: Current progress in molecular signaling and therapeutics
(Elsevier Ireland Ltd, 2023-10-30)Alzheimer's Disease (AD) is one of the most devastating age-related disorder causing significant social and economic burden worldwide. It affects the cognitive and social behavior of individuals and characterized by ... -
Assessment of tRNAThr and tRNAGln Variants and Mitochondrial Functionality in Parkinson�s Disease (PD) Patients of Tamil Nadu Population
(Springer, 2023-10-17)Parkinson�s disease (PD) is speculated with genetic and environmental factors. At molecular level, the mitochondrial impact is stated to be one of the causative reasons for PD. In this study, we investigated the mitochondrial ... -
Probing interaction of atherogenic lysophosphatidylcholine with functionalized graphene nanosheets: theoretical modelling and experimental validation
(Springer Science and Business Media Deutschland GmbH, 2023-09-09)Context: The potential of graphene derivatives for theranostic applications depends on their compatibility with cellular and biomolecular components. Lysophosphatidylcholine (LPC), a lipid component present in oxidized ... -
Retinal Changes in Parkinson�s Disease: A Non-invasive Biomarker for Early Diagnosis
(Springer, 2023-10-13)Parkinson�s disease (PD) is caused due to degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) which leads to the depletion of dopamine in the body. The lack of dopamine is mainly due to ... -
Platelet-derived microvesicles induce intracellular calcium mobilization in human platelets
(John Wiley and Sons Inc, 2023-08-31)Platelet-derived microvesicles (PMVs) represent a significant proportion of microvesicles in circulation and have been linked to various pathophysiological complications. Recent research suggests that PMVs carry significant ... -
Understanding the impact of sociosexual interactions on sleep using Drosophila melanogaster as a model organism
(Frontiers Media SA, 2023-08-21)Sleep is conserved across species, and it is believed that a fixed amount of sleep is needed for normal neurobiological functions. Sleep rebound follows sleep deprivation; however, continuous sleep deprivation for longer ... -
Epicardial adipose tissue and cardiac lipotoxicity: A review
(Elsevier Inc., 2023-07-05)Epicardial adipose tissue (EAT) has morphological and physiological contiguity with the myocardium and coronary arteries, making it a visceral fat deposit with some unique properties. Under normal circumstances, EAT exhibits ... -
Recent advances in understanding brain cancer metabolomics: a review
(Springer, 2023-07-10)Regardless of the significant progress made in surgical techniques and adjuvant therapies, brain tumors are a major contributor to cancer-related morbidity and mortality in both pediatric and adult populations. Gliomas ... -
A comprehensive review on the decabromodiphenyl ether (BDE-209)-induced male reproductive toxicity: Evidences from rodent studies
(Elsevier B.V., 2023-08-02)Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants (BFRs), are employed in various manufactured products to prevent fires, slow down their spread and reduce the resulting damages. Decabromodiphenyl ... -
Molecular mechanisms of alcohol's effects on the human body: A review and update
(John Wiley and Sons Inc, 2023-08-14)Alcohol consumption has been linked to numerous negative health outcomes although it has some beneficial effects on moderate dosages, the most severe of which being alcohol-induced hepatitis. The number of people dying ... -
Plausible Role of Mitochondrial DNA Copy Number in Neurodegeneration�a Need for Therapeutic Approach in Parkinson�s Disease (PD)
(Springer, 2023-07-31)Parkinson�s disease (PD) is an advancing age-associated progressive brain disorder which has various diverse factors, among them mitochondrial dysfunction involves in dopaminergic (DA) degeneration. Aging causes a rise in ... -
HPV-associated cancers: insights into the mechanistic scenario and latest updates
(Springer, 2023-06-26)Cancer and related diseases are the second leading cause of death worldwide. The human papillomavirus (HPV) is an infectious agent that can be spread mainly through sexual contact and has been linked to several malignancies ... -
Application of curcumin nanoformulations to target folic acid receptor in cancer: Recent trends and advances
(Academic Press Inc., 2023-06-20)Curcumin, derived from turmeric, has a strong anticancer potential known for millennia. The development of this phytochemical as a medicine has been hampered by several significant deficiencies, including its poor water ... -
Artificial intelligence in heavy metals detection: Methodological and ethical challenges
(Elsevier B.V., 2023-07-02)Heavy metals (HMs) are metallic substances. They enter biotic and abiotic systems through natural and human activities. These HMs have an impact on the atmosphere, soil, and groundwater, and they also affect all living ... -
A deeper understanding about the role of uranium toxicity in neurodegeneration
(Academic Press Inc., 2023-06-15)Natural deposits and human-caused releases of uranium have led to its contamination in the nature. Toxic environmental contaminants such as uranium that harm cerebral processes specifically target the brain. Numerous ... -
Connecting the Link between Oxidative Stress, Dietary Antioxidants and Hypertension
(CRC Press, 2023-06-12)Cardiovascular disorders such as hypertension, coronary heart disease (CHD), cerebrovascular disease, etc. accounts for millions of deaths per year and among these, hypertension (i.e. increased blood pressure) acts as a ... -
Unveiling the mechanism of platelet dysfunction in Parkinson's disease: The effect of 6-hydroxydopamine on human blood platelets
(Elsevier Ltd, 2023-05-22)Introduction: Parkinson's disease (PD) is a progressive neuronal illness often linked to increased cardiovascular complications, such as myocardial infarction, cardiomyopathy, congestive heart failure, and coronary heart ... -
In silico evaluation of natural compounds to confirm their anti-DNA gyrase activity
(Springer, 2023-06-03)The slow clearance of bacteria owing to drug resistance to the currently available antibiotics has been a global public health issue. The development of antibiotic resistance in Staphylococcus aureus has become prevalent ... -
Onco-Pathogen Mediated Cancer Progression and Associated Signaling Pathways in Cancer Development
(MDPI, 2023-05-28)Infection with viruses, bacteria, and parasites are thought to be the underlying cause of about 8�17% of the world�s cancer burden, i.e., approximately one in every five malignancies globally is caused by an infectious ...