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Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase
(American Society for Biochemistry and Molecular Biology Inc., 2017)
Nischarin (Nisch) is a key protein functioning as a molecular scaffold and thereby hosting interactions with several protein partners. To explore the physiological importance of Nisch, here we generated Nisch loss-of-function ...
Nischarin regulates focal adhesion and Invadopodia formation in breast cancer cells
(BioMed Central Ltd., 2018)
Background: During metastasis, tumor cells move through the tracks of extracellular matrix (ECM). Focal adhesions (FAs) are the protein complexes that link the cell cytoskeleton to the ECM and their presence is necessary ...