Browsing Theses and Dissertation by Title
Now showing items 166-185 of 395
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Identification of Curcuma longa phytochemicals as a novel inhibitor of proteins involved in Allergic Rhinitis
(Central University of Punjab, 2018)Histamine and other chemical mediators play crucial role in the disease development condition of allergic rhinitis. Allergic rhinitis is a mild or severe allergic condition due to the interaction of allergens with the IgE ... -
Identification Of Ganoderic Acids And Derivatives From Fruiting Bodies Of Ganoderma Lucidum
(Central University of Punjab, 2018)Ganoderic acids and other bioactive triterpene metabolites from crude extract of wood decaying fungus Ganoderma lucidum from two different hosts Acacia and Azadirachta were to be isolated as proposed. The method for ... -
Identification of natural inhibitors of proteins involved in the pathology of Parkinson's disease
(Central University of Punjab, 2018)Parkinson's disease (PD) is a progressive neurodegenerative disorder caused due to the lack of dopamine in the brain. Different drug therapies are available for PD showing excellent efficiency, but most of them are cost ... -
Identification of Novel lncRNA in Breast Cancer Cell Line
(Central University of Punjab, 2018)Long non-coding RNA(lncRNA) is RNA transcript having size of more 200 nucleotides and low number of exons are present due to which it expressed at lower level in specific tissues. Mainly the lncRNA is involved in gene ... -
Identification of Novel Natural Inhibitors Of Proteins Involved In Cancer Cell Stemness
(Central University of Punjab, 2018)Cancer stem cells (CSCs) are a small subpopulation of cells identified in a variety of tumors that are capable of self-renewal, differentiation and have the unique property to evade radiotherapy and chemotherapy. CSCs are ... -
Identification of some novel natural inhibitors of proteins in the life cycle of the malarial parasite
(Central University of Punjab, 2018)Antimalarial phytoconstituents were identified and analysed.We studied receptor based molecular docking of protein drug targets( Plasmepsin 2 (1lf2),HSP90 (3k60), PfATPase ( 1u5n), Human orotidine 5 - decarboxylase domain ... -
Identifying novel miRNA targets of anticancer drugs in normoxic and hypoxic condition
(Central University of Punjab, 2018)Breast cancer has become the prevailing cause of death, so the research for their treatment has become advanced day by day. Breast cancer behaves differently in normoxic and hypoxic condition so does the anticancer drugs ... -
Imidazole based compunds: Synethesis and in vitro anticancer screening
(Central University of Punjab, 2013)Imidazole is an important five-membered aromatic heterocycle widely present in natural products and synthetic molecules. The unique structural feature of imidazole ring with desirable electron rich characteristic is ... -
Impact Assessment Of Judicial Approach Towards Tender Process In India
(Central University of Punjab, 2018)With the growth of population the need for infrastructural and other development has also arisen much and it has created an over burdened responsibility upon the government. Thus, the government had in order to come out ... -
Impact of Human Elephant Conflict on People's Wellbeing in West Bengal
(Central University of Punjab, 2018)One of the major issues in wildlife management is Human-Wildlife conflict. Over the last two decades, the problem has only increased because of growing population, economic activities, both in privately and publicly run. ... -
Impact of laws, awareness and local participation in prevention and control of crop residue burning: A case study of bathinda district
(Central University of Punjab, 2018)The present study entitled 'Impact of Laws, Awareness and Local Participation in Prevention and Control of Crop Residue Burning: A Case Study of Bathinda District' is an attempt to explore the serious environmental and ... -
Impact of mitochondrial transplantation on cancer cells
(Central University of Punjab, 2014)Mitochondria, the powerhouse of the cell, are small granular or filamentous bodies associated significantly with cellular respiration and are the main sources of energy, due to which they are present in maximum number in ... -
Implementation Of Laws & Policies On Mobile Towers & Mobile Phone Radiation Levels In India: A Case Study Of Bathinda City
(Central University of Punjab, 2018)Mobile phones are now an inevitable part of our day to day life. Besides being a communication device it is also being used for information and entertainment purposes. With the advancement in the telecommunication sector, ... -
Implication of Methods and Techniques of Relaxation for Investigating the Iron release mechanism of Transferrin
(Central University of Punjab, 2018)Transferrins (Tfs, serum transferring (sTf), ovotransferrin (oTf), lactotransferrin(Lf)) are bilobal iron binding glycoprotein's. In the absence of iron, the two lobs are in open conformation. Upon complex formation with ... -
Improved 2ACK scheme for reducing routing overhead in manet's
(Central University of Punjab, 2014)An autonomous collection of mobile nodes communicating with each other via wireless links either directly or indirectly or relying on other nodes forms the mobile adhoc network (MANET). The routing protocols in MANET are ... -
Improved and rule scheme to increase lifetime of wireless sensor networks
(Central University of Punjab, 2014)Wireless sensor network (WSN) is a network of small light weight wireless nodes which are highly distributed and deployed in large numbers. The sensor nodes scan the environment and provide useful information to the user ... -
In Silico Design Of Compounds As Sglt2 Inhibitors
(Central University of Punjab, 2018)SGLT2 inhibitors (SGLT2i) are the current novel therapeutic approach expected to control the growing threat of type 2 diabetes mellitus (T2DM). With comparatively least reported side effects, SGLT2i (gliflozins) have been ... -
In silico identification of natural anticancer product and their efficacy in breast cancer cells and cancer stem like cells
(Central University of Punjab, 2020)Breast cancer is the most commonly diagnosed lethal cancer in women worldwide. Notch signaling pathway is directly linked to breast cancer recurrence and aggressiveness. Natural remedies are becoming a prime choice to ... -
In Silico Identification of Novel Natural Inhibitors Of Carbohydrate Metabolic Pathway In Cancer Cells
(Central University of Punjab, 2018)Carbohydrate metabolism in cancer cells is linked to the 'Warburg Effect' which states that, under aerobic conditions, cancer cells metabolize approximately ten fold more glucose to lactate in a given time than normal ... -
In vitro and In silico study of Essential oil Components from Eucalyptus tereticornis as Antibacterial agents
(Central University of Punjab, 2018)Many essential oils are known for their antimicrobial activity and the main target is bacterial cell membrane which is important for bacterial viability and hence the study was done to find the target and effective binding ...