Browsing Biochemistry and Microbial Sciences-Research Publications by Author "Kumar S."
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Bulbine frutescens phytochemical inhibits notch signaling pathway and induces apoptosis in triple negative and luminal breast cancer cells
Kushwaha P.P.; Vardhan P.S.; Kapewangolo P.; Shuaib M.; Prajapati S.K.; Singh A.K.; Kumar S. (Elsevier Inc., 2019)Breast cancer (BCa) is the most commonly diagnosed lethal cancer in women worldwide. Notch signaling pathway is directly linked to BCa recurrence and aggressiveness. Natural remedies are becoming a prime choice to overcome ... -
Lysine and ?-Aminoisobutyric Acid Conjugated Bioinspired Polydopamine Surfaces for the Enhanced Antibacterial Performance of the Foley Catheter
Patel K.; Kushwaha P.; Kumar S.; Kumar R. (American Chemical Society, 2019)Microbial adhesion onto implanted devices was reduced by the immobilization of amino acid lysine and ?-aminoisobutyric acid to polydopamine functionalized PET films and Foley catheters. The polydopamine functionalized film ... -
MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer
Kushwaha P.P.; Gupta S.; Singh A.K.; Prajapati K.S.; Shuaib M.; Kumar S. (Mary Ann Liebert Inc., 2020)Significance: Reactive oxygen species (ROS) production occurs primarily in the mitochondria as a by-product of cellular metabolism. ROS are also produced by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in ...