Browsing Biochemistry and Microbial Sciences-Research Publications by Subject "Cell culture"

Now showing items 1-2 of 2

    • Naphthylisoindolinone alkaloids: the first ring-contracted naphthylisoquinolines, from the tropical liana Ancistrocladus abbreviatus, with cytotoxic activity 

      Fayez, Shaimaa; Bruhn, Torsten; Feineis, Doris; Assi, Laurent Ak�; Kushwaha, Prem Prakash; Kumar, Shashank; Bringmann, Gerhard (Royal Society of Chemistry, 2022-10-12)
      The West African liana Ancistrocladus abbreviatus is a rich source of structurally most diverse naphthylisoquinoline alkaloids. From its roots, a series of four novel representatives, named ancistrobrevolines A-D (14-17) ...

    • Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase 

      Dong, Shengli; Baranwal, Somesh; Garcia, Anapatricia; Serrano-Gomez, Silvia; Eastlack, Steven; Iwakuma, Tomoo; Mercante, Donald; Mauvais-Jarvis, Franck; Alahari, Suresh K.; Dong, S.; Baranwal, S.; Garcia, A.; Serrano-Gomez, S.J.; Eastlack, S.; Iwakuma, T.; Mercante, D.; Mauvais-Jarvis, F.; Alahari, S.K. (American Society for Biochemistry and Molecular Biology Inc., 2017)
      Nischarin (Nisch) is a key protein functioning as a molecular scaffold and thereby hosting interactions with several protein partners. To explore the physiological importance of Nisch, here we generated Nisch loss-of-function ...