Browsing Biochemistry and Microbial Sciences-Research Publications by Subject "cancer"
Now showing items 1-6 of 6
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Discovery of Natural Anti-Apoptotic Protein Inhibitor Using Molecular Docking and MM-GBSA Approach: An Anticancer Intervention
(AMG Transcend Association, 2022-12-27)Apoptosis is a programmed molecular phenomenon in normal cells, and "evading apoptosis" is a hallmark of cancer. Overexpression of anti-apoptotic BCL-2 promotes cancer cell survival, leading to tumor formation, its maintenance ... -
Emerging Role of Migration and Invasion Enhancer 1 (MIEN1) in Cancer Progression and Metastasis
(Frontiers Media S.A., 2019)Tumor metastasis is a sequential event accounting for numerous cancer-related fatalities worldwide. The process of metastasis serially involves invasion, intravasation, extravasation, and tumor growth at the secondary site. ... -
MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer
(Mary Ann Liebert Inc., 2020)Significance: Reactive oxygen species (ROS) production occurs primarily in the mitochondria as a by-product of cellular metabolism. ROS are also produced by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in ... -
Multifarious Effects of Arsenic on Plants and Strategies for Mitigation
(MDPI, 2023-02-09)Arsenic contamination in soil and water is a major problem worldwide. Inorganic arsenic is widely present as arsenate and arsenite. Arsenic is transferred to crops through the soil and irrigation water. It is reported to ... -
Naringin dihydrochalcone potentially binds to catalytic domain of matrix metalloproteinase-2: molecular docking, MM-GBSA, and molecular dynamics simulation approach
(Taylor and Francis Ltd., 2022-09-01)Matrix metalloproteinase-2 (MMP2), an extracellular matrix remodulating protein�s increased activity causes cancer-metastasis. Potential MMP2 inhibitors showed sever side-effects in clinical trials. Present study is focused ... -
SNHG12: An LncRNA as a Potential Therapeutic Target and Biomarker for Human Cancer
(Frontiers Media S.A., 2019)Limitations in current diagnostic procedures warrant identification of new methodologies to improve diagnoses of cancer patients. In this context, long non-coding RNAs (lncRNAs) have emerged as stable biomarkers which are ...