Now showing items 1-8 of 8

    • The Epigenetics of Noncoding RNA 

      Chhabra, Ravindresh (Elsevier, 2022-09-16)
      DNA, RNA, and the proteins are the major players in the flow of genetic information. Out of these, RNA is the most versatile biomolecule as it exists in multiple forms and each form carries out specified functions in the ...
    • Identification of cancer stemness related miRNA(s) using integrated bioinformatics analysis and in vitro validation 

      Prajapati, Kumari Sunita; Shuaib, Mohd; Kushwaha, Prem Prakash; Singh, Atul Kumar; Kumar, Shsahank (Springer Science and Business Media Deutschland GmbH, 2021-09-23)
      The stemness property of cells allows them to sustain their lineage, differentiation, proliferation, and regeneration. MicroRNAs are small non-coding RNAs known to regulate the stemness property of cells by regulating the ...
    • The journey of noncoding RNA from bench to clinic 

      Chhabra, Ravindresh (Elsevier, 2021-01-30)
      The discovery of noncoding RNA (ncRNA) in the 90s completely changed our understanding of gene regulation. The ncRNAs specialize in regulating the gene expression, which enables them to induce a remarkable change in cellular ...
    • MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer 

      Kushwaha P.P.; Gupta S.; Singh A.K.; Prajapati K.S.; Shuaib M.; Kumar S. (Mary Ann Liebert Inc., 2020)
      Significance: Reactive oxygen species (ROS) production occurs primarily in the mitochondria as a by-product of cellular metabolism. ROS are also produced by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in ...
    • Obesity and Cancer 

      Kumar, Shashank; Gupta, Sanjay (Springer Singapore, 2021-07-18)
      This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development ...
    • A review of chromium (Cr) epigenetic toxicity and health hazards 

      Iyer, Mahalaxmi; Anand, Uttpal; Thiruvenkataswamy, Saranya; Babu, Harysh Winster Suresh; Narayanasamy, Arul; Prajapati, Vijay Kumar; Tiwari, Chandan Kumar; Gopalakrishnan, Abilash Valsala; Bontempi, Elza; Sonne, Christian; Barcel�, Dami�; Vellingiri, Balachandar (Elsevier B.V., 2023-04-17)
      Carcinogenic metals affect a variety of cellular processes, causing oxidative stress and cancer. The widespread distribution of these metals caused by industrial, residential, agricultural, medical, and technical activities ...
    • SNHG12: An LncRNA as a Potential Therapeutic Target and Biomarker for Human Cancer 

      Tamang, S; Acharya, V; Roy, D; Sharma, R; Aryaa, A; Sharma, U; Khandelwal, A; Prakash, H; Vasquez, K.M; Jain, A. (Frontiers Media S.A., 2019)
      Limitations in current diagnostic procedures warrant identification of new methodologies to improve diagnoses of cancer patients. In this context, long non-coding RNAs (lncRNAs) have emerged as stable biomarkers which are ...
    • Withaferin A mediated changes of miRNA expression in breast cancer-derived mammospheres 

      Prajapati, Kumari Sunita; Shuaib, Mohd.; Gupta, Sanjay; Kumar, Shashank (John Wiley and Sons Inc, 2022-06-30)
      Breast cancer is a heterogeneous disease consisting of atypical cell populations that share stem cell-like characteristics associated with therapeutic resistance, disease relapse, and poor clinical outcome. MicroRNAs ...