Cancer is the ruling cause of mortality worldwide. Chemotherapeutic toxicity and drug resistance have provided impulsion for the formulation of new anticancer agents. Receptor tyrosine kinases (RTKs) are the most activated ...

Biological and biosimilar drugs Medicines that are derived from living cells/organisms are known as biological medicines. They consist of of highly complex molecular entities difficult to characterize. Certain degree ...

For normal cell division, one time replication origin firing is mandatory. The mutual interaction and levels of Cdt1 and geminin (GMNN) proteins are known to be involved in this regulatory mechanism. Imbalance between these ...

Despite rapid strides in the medical and technological fields during the last four decades including the development of nucleic acid and protein-based biomarkers, the mortality still remains a burning problem because of ...

Cancer is a group of disease characterized by the uncontrolled growth and spread of abnormal cells which may lead to death. According to a report by GLOBOCAN the number of new cancer cases would increase to 19.3 million ...

Organ is composed of special type of tissue and cells. Deficits in functionality and number of particular cells lead to the development of various type of human disease such as diabetes, neurological disease, cardiovascular, ...

Aims: Breast cancer is the second most common cancer in the world and, by far, the most frequent cancer among women. Scientific literature has hypothesized the association of ACE I/D polymorphism with breast cancer for ...

The morphology and physicochemical properties of polydopamine are not totally inherent and undergo changes with differing reaction conditions like the choice of solvent used for polymerization. The polymerisation of dopamine ...

Breast cancer is the second most prominent reason of cancer death in women after lung cancer, and it accounts for 25.2% of all cancer in women [1]. In the US, approximately about one in eight women (12%) develop invasive ...

DNA replicates in a timely manner with each cell division. Multiple proteins and factors are involved in the initiation of DNA replication including a dynamic interaction between Cdc10-dependent transcript (Cdt1) and Geminin ...