Browsing Zoology-Research Publications by Title
Now showing items 64-83 of 173
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Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets
(SAGE Publications Inc., 2021-12-14)With the dramatic increase in cancer incidence all over the world in the last decades, studies on identifying novel efficient anti-cancer agents have been intensified. Historically, natural products have represented one ... -
Gametogenic and steroidogenic action of kisspeptin-10 in the Asian catfish, Clarias batrachus: Putative underlying mechanistic cascade
(Elsevier Inc., 2021-06-28)Unlike mammals, two kisspeptins genes encoding, kiss1 and kiss2 are detected in fishes with highly varied and contradictory difference in their reproductive activities. The present study was undertaken to examine the direct ... -
Geminin a multi task protein involved in cancer pathophysiology and developmental process: A review
(Elsevier B.V., 2016)DNA replicates in a timely manner with each cell division. Multiple proteins and factors are involved in the initiation of DNA replication including a dynamic interaction between Cdc10-dependent transcript (Cdt1) and Geminin ... -
Genetic and epigenetic markers in colorectal cancer screening: recent advances
(Taylor & Francis, 2017)Introduction: Colorectal cancer (CRC) is a heterogenous disease which develops from benign intraepithelial lesions known as adenomas to malignant carcinomas. Acquired alterations in Wnt signaling, TGFβ, MAPK pathway genes ... -
Ginkgolide B Revamps Neuroprotective Role of Apurinic/Apyrimidinic Endonuclease 1 and Mitochondrial Oxidative Phosphorylation Against Ab 25–35 -Induced Neurotoxicity in Human Neuroblastoma Cells
(Wiley, 2015)Accumulating evidence points to roles for oxidative stress, amyloid beta (Aβ), and mitochondrial dysfunction in the pathogenesis of Alzheimer's disease (AD). In neurons, the base excision repair pathway is the predominant ... -
Glycyrrhiza glabra (Licorice) root extract attenuates doxorubicin-induced cardiotoxicity via alleviating oxidative stress and stabilising the cardiac health in H9c2 cardiomyocytes
(Elsevier, 2020)Ethnopharmacological relevance: Doxorubicin (DOX) is an effective anti-neoplastic drug, however; it has downside effects on cardiac health and other vital organs. The herbal remedies used in day to day life may have a ... -
Gut-specific arylphorin mediates midgut regenerative response against Cry-induced damage in Achaea janata
(Elsevier Inc., 2021-04-13)Development of insect resistance to biopesticides is a current and pertinent global issue. Earlier, it was established that lepidopteran larvae can recover from Bt intoxication via a midgut regenerative response and ... -
H 2 O 2 sensing through electrochemically deposited thionine coated ITO thin film
(Cellular and Molecular Biology Association, 2017)Progression and initiation of different diseases including pulmonary diseases, alzheimer's and tumors are linked with the oxidative stress, an important cause of cell damage. Different antioxidant enzymes are involved in ... -
H2 O2 sensing through electrochemically deposited thionine coated ITO thin film
(CMB Association Publications, 2017)Progression and initiation of different diseases including pulmonary diseases, alzheimer’s and tumors are linked with the oxidative stress, an important cause of cell damage. Different antioxidant enzymes are involved in ... -
Heavy Metal and Metalloid Contamination in Food and Emerging Technologies for Its Detection
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-01-09)Heavy metal and metalloid poisoning in the environment and food has piqued the public�s interest since it poses significant hazards to the ecological system and human health. In food, several metals, including cadmium (Cd), ... -
Herbal Remedies for Improving Cancer Treatment Through Modulation of Redox Balance
(Springer Singapore, 2022-09-28)The redox modulation induced by oxidative stress is one of the major cause of the metabolic and inflammatory disorders including cancer. The reactive oxygen species (ROS) produced by various sources in the cell shift the ... -
Hormones of hypothalamus and ageing
(Springer, 2018)Hypothalamus being the master regulator of the vertebrate endocrine system undergoes many adjustments/alterations which body makes during the course of aging. Moreover, the endocrinological basis of aging in male and female ... -
Host sphingolipids: Perspective immune adjuvant for controlling SARS-CoV-2 infection for managing COVID-19 disease
(Elsevier Inc., 2020-11-02)Sphingolipids are potent bioactive agents involved in the pathogenesis of various respiratory bacterial infections. To date, several sphingolipid derivatives are known, but S1P (Sphingosine-1-phosphate) and Ceramide are ... -
HPV-associated cancers: insights into the mechanistic scenario and latest updates
(Springer, 2023-06-26)Cancer and related diseases are the second leading cause of death worldwide. The human papillomavirus (HPV) is an infectious agent that can be spread mainly through sexual contact and has been linked to several malignancies ... -
Human apurinic/apyrimidinic endonuclease (APE1) is acetylated at DNA damage sites in chromatin, and acetylation modulates its DNA repair activity
(American Society for Microbiology, 2016)Apurinic/apyrimidinic (AP) sites, the most frequently formed DNA lesions in the genome, inhibit transcription and block replication. The primary enzyme that repairs AP sites in mammalian cells is the AP endonuclease (APE1), ... -
Hydrogen peroxide-induced oxidative stress and its impact on innate immune responses in lung carcinoma A549 cells
(Springer, 2019)The immune responses, involved in recognition of cancer-specific antigens, are of particular interest as this may provide major leads towards developing new vaccines and antibody therapies against cancer. An effective ... -
Identification of novel indole based heterocycles as selective estrogen receptor modulator.
(Elsevier, 2018)In the present study, we have designed and synthesized indole derivatives by coalescing the indole nucleus with chromene carbonitrile and dihydropyridine nucleus. Two compounds 5c and 6d were selected from series I and II ... -
The imminent role of microRNAs in salivary adenoid cystic carcinoma
(Neoplasia Press, Inc., 2022-11-04)Unfortunately, despite the severe problem associated with salivary adenoid cystic carcinoma (SACC), it has not been studied in detail yet. Therefore, the time has come to understand the oncogenic cause of SACC and find the ... -
Impact of noncoding RNAs on cancer directed immune therapies: Now then and forever
(John Wiley and Sons Inc, 2022-04-30)Accumulating evidence demonstrates that the host genome's epigenetic modifications are essential for living organisms to adapt to extreme conditions. DNA methylation, covalent modifications of histone and interassociation ... -
The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
(MDPI, 2023-01-16)As a complex endocrine and metabolic condition, polycystic ovarian syndrome (PCOS) affects women�s reproductive health. These common symptoms include hirsutism, hyperandrogenism, ovulatory dysfunction, irregular menstruation, ...