Browsing Zoology-Research Publications by Title
Now showing items 21-40 of 173
-
Bio-analytical applications of nicking endonucleases assisted signal-amplification strategies for detection of cancer biomarkers -DNA methyl transferase and microRNA
(Elsevier Ltd, 2019)The low concentrations of cancer biomarkers in the blood have limited the utility of quantitative bioassays developed for the purpose. The advent of nicking endonucleases (NEases) as signal amplification tools have greatly ... -
Bioactive peptides for boosting stem cell culture platform: Methods and applications
(Elsevier Masson s.r.l., 2023-02-09)Peptides, short protein fragments, can emulate the functions of their full-length native counterparts. Peptides are considered potent recombinant protein alternatives due to their specificity, high stability, low production ... -
A BIOCHEMICAL STUDY TO EVALUATE THE ROLE OF APURINIC/APYRIMIDINIC ENDONUCLEASE 1 (APE1) IN LUNG CANCER PROGRESSION
(Central University of Punjab, 2018)Globally, lung cancer has the highest incidence and mortality rate. Environmental factors such as chlorpyrifos (CP) and monocrotophos (MCP), widely used organophosphate pesticides (OPPs), and are reported to be involved ... -
Biodegradable nanoparticulate co-delivery of flavonoid and doxorubicin: Mechanistic exploration and evaluation of anticancer effect in vitro and in vivo
(Elsevier Ltd, 2021-07-30)The proposed study involves delivering drug/bioactive using a single nanoplatform based on poly lactic-co-glycolic acid (PLGA) for better efficacy, synergistic effect, and reduced toxicity. PLGA was conjugated to doxorubicin ... -
Bioremediation: A favorable perspective to eliminate heavy metals from polluted soil
(Elsevier, 2022-09-30)The heavy metal contamination in the environment causes serious risk and long-term lethal effects to all living organisms due to their ability to show toxicity at low concentrations. The bio-magnification of heavy metals ... -
Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies
(Elsevier Ltd, 2017)Breast cancer is highly prevalent in females and accounts for second highest number of deaths, worldwide. Cumbersome, expensive and time consuming detection techniques presently available for detection of breast cancer ... -
Biosynthesis of Zinc Oxide Nanoparticles Using Catharanthus Roseus Leaves and Their Therapeutic Response in Breast Cancer (MDA-MB-231) Cells
(Routledge, 2021-07-26)As the current study reports the utilization of the leaf extract of Catharanthus roseus (C.roseus) for the biological synthesis of zinc oxide nanoparticles (ZnO NPs) because of the importance of the importance of health ... -
Blood Coagulation System and Carbon-Based Nanoengineering for Biomedical Application
(Springer Nature, 2021-10-01)Carbon-based nanomaterials (CBNs) acquired unique physiochemical properties, due to which they were examined for various biomedical applications such as bio-imaging, bio-sensing, targeted drug delivery, etc. CBNs first ... -
Cancer Susceptibility Candidate 9 (CASC9): A Novel Targetable Long Noncoding RNA in Cancer Treatment
(Neoplasia Press, Inc., 2020)Based on epidemiological data provided by the World Health Organization (2018), cancer is the second most prevalent cause of death worldwide. Several factors are thought to contribute to the high mortality rate in cancer ... -
CHAPTER 9: Nanomaterial-Blood Interactions: A Biomedical Perspective
(Royal Society of Chemistry, 2019)Within the short span of a decade, nanotechnology has gained tremendous recognition in diagnostic and therapeutic applications owing to its unique physiochemical properties. Whenever nanomaterials (NMs) are intravenously ... -
Circulating long non-coding RNA EWSAT1 acts as a liquid biopsy marker for esophageal squamous cell carcinoma: A pilot study
(KeAi Communications Co., 2023-10-28)The widespread public health problem of esophageal squamous cell carcinoma (ESCC) is the cause of an increasing number of deaths each year due to delayed diagnosis. Therefore, we require specific and sensitive new biomarkers ... -
Circulating Long Non-Coding RNAs LINC00324 and LOC100507053 as Potential Liquid Biopsy Markers for Esophageal Squamous Cell Carcinoma: A Pilot Study
(Frontiers Media S.A., 2022-02-14)Background: Despite the availability of advanced technology to detect and treat esophageal squamous cell carcinoma (ESCC), the 5-year survival rate of ESCC patients is still meager. Recently, long non-coding RNAs (lncRNAs) ... -
Circulating microRNA-590-5p functions as a liquid biopsy marker in non-small cell lung cancer
(Blackwell Publishing Ltd, 2020)Despite the availability of various diagnostic procedures, a tissue biopsy is still indispensable for the routine diagnosis of lung cancer. However, inaccurate diagnoses can occur, leading to inefficient cancer management. ... -
Circulating miR-320a Acts as a Tumor Suppressor and Prognostic Factor in Non-small Cell Lung Cancer
(Frontiers Media S.A., 2021-03-23)Dysregulated expression profiles of microRNAs (miRNAs) have been observed in several types of cancer, including non-small cell lung cancer (NSCLC); however, the diagnostic and prognostic potential of circulating miRNAs in ... -
Clinical potential of long non-coding RNA LINC01133 as a promising biomarker and therapeutic target in cancers
(Newlands Press Ltd, 2022-02-23)Recently, long intergenic non-protein coding RNA 01133 (LINC01133) was identified as a novel transcript in cancers. It modulates various hallmarks of cancers and acts as oncogenic in some cancers while tumor-suppressive ... -
Cloning and characterization of a riboflavin-binding hexamerin from the larval fat body of a lepidopteran stored grain pest, Corcyra cephalonica
(Elsevier Inc., 2016)In the present study, a riboflavin-binding hexamerin (RbHex) was cloned and characterized from the larval fat body of Corcyra cephalonica. The complete cDNA (2121 bp) encodes a 706-amino acid protein with a molecular mass ... -
Cloning, characterization and transmission blocking potential of midgut carboxypeptidase A in Anopheles stephensi
(Elsevier B.V., 2017)Transmission-blocking vaccines (TBV) interrupt malaria parasite transmission and hence form an important component for malaria eradication. Mosquito midgut exopeptidases such as aminopeptidase N & carboxypeptidase B have ... -
Cloning, expression and in vitro validation of chimeric multi epitope vaccine candidate against visceral leishmaniasis infection
(Elsevier Inc., 2023-04-11)Visceral Leishmaniasis or Kala-Azar is one of the most severe and deadly neglected tropical disease caused by the Leishmania parasite. A few number of vaccines are going through different phases in clinical trial but failing ... -
A comprehensive review on the decabromodiphenyl ether (BDE-209)-induced male reproductive toxicity: Evidences from rodent studies
(Elsevier B.V., 2023-08-02)Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants (BFRs), are employed in various manufactured products to prevent fires, slow down their spread and reduce the resulting damages. Decabromodiphenyl ...