Browsing Zoology-Research Publications by Issue Date
Now showing items 21-40 of 173
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Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation
(Impact Journals, 2016)Mammalian apurinic/apyrimidinic (AP) endonuclease 1 (APE1), a ubiquitous and multifunctional protein, plays an essential role in the repair of both endogenous and drug-induced DNA damages in the genome. Unlike its E.coli ... -
The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer
(Impact Journals LLC, 2017)Chemoresistance is one of the major hurdles in the treatment of breast cancer, which limits the effect of both targeted and conventional therapies in clinical settings. Therefore, understanding the mechanisms underpinning ... -
Genetic and epigenetic markers in colorectal cancer screening: recent advances
(Taylor & Francis, 2017)Introduction: Colorectal cancer (CRC) is a heterogenous disease which develops from benign intraepithelial lesions known as adenomas to malignant carcinomas. Acquired alterations in Wnt signaling, TGFβ, MAPK pathway genes ... -
Microbial xylanases and their industrial application in pulp and paper biobleaching: a review
(Springer Verlag, 2017)Xylanases are hydrolytic enzymes which cleave the ?-1, 4 backbone of the complex plant cell wall polysaccharide xylan. Xylan is the major hemicellulosic constituent found in soft and hard food. It is the next most abundant ... -
H2 O2 sensing through electrochemically deposited thionine coated ITO thin film
(CMB Association Publications, 2017)Progression and initiation of different diseases including pulmonary diseases, alzheimer’s and tumors are linked with the oxidative stress, an important cause of cell damage. Different antioxidant enzymes are involved in ... -
The emerging role of long non-coding RNA in gallbladder cancer pathogenesis
(Elsevier B.V., 2017)Gallbladder cancer (GBC) is the most common and aggressive form of biliary tract carcinoma with an alarmingly low 5-year survival rate. Despite its high mortality rate, the underlying mechanisms of GBC pathogenesis are not ... -
Role of sphingosine-1-phosphate in mast cell functions and asthma and its regulation by non-coding RNA
(Frontiers Media S.A., 2017)Sphingolipid metabolites are emerging as important signaling molecules in allergic diseases specifically asthma. One of the sphingolipid metabolite, sphingosine-1-phosphate (S1P), is involved in cell differentiation, ... -
Larval mid-gut responses to sub-lethal dose of cry toxin in lepidopteran pest Achaea janata
(Frontiers Media S.A., 2017)The lack of homogeneity in field application of Bacillus thuringiensis formulation often results in ingestion of sub-lethal doses of the biopesticide by a fraction of pest population and there by promotes the toxin tolerance ... -
Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors
(Nature Publishing Group, 2017)The guidance protein Semaphorin7A (Sema7A) is required for the proper development of the immune and nervous systems. Despite strong expression in the mature brain, the role of Sema7A in the adult remains poorly defined. ... -
Cloning, characterization and transmission blocking potential of midgut carboxypeptidase A in Anopheles stephensi
(Elsevier B.V., 2017)Transmission-blocking vaccines (TBV) interrupt malaria parasite transmission and hence form an important component for malaria eradication. Mosquito midgut exopeptidases such as aminopeptidase N & carboxypeptidase B have ... -
Fat body remodeling in Spodoptera litura F. (Lepidoptera: Noctuidae) during postembryonic development2017
(Association for Advancement of Entomology, 2017)During insect metamorphosis, larval structures including fat body are replaced by the adult ones. This process involves lysosomal enzyme-mediated remodeling of fat body. The objective of this study is to characterize the ... -
Biosensors for breast cancer diagnosis: A review of bioreceptors, biotransducers and signal amplification strategies
(Elsevier Ltd, 2017)Breast cancer is highly prevalent in females and accounts for second highest number of deaths, worldwide. Cumbersome, expensive and time consuming detection techniques presently available for detection of breast cancer ... -
An in vitro study ascertaining the role of H2O2 and glucose oxidase in modulation of antioxidant potential and cancer cell survival mechanisms in glioblastoma U-87 MG cells
(Springer New York LLC, 2017)Glial cells protect themselves from the elevated reactive oxygen species (ROS) via developing unusual mechanisms to maintain the genomic stability, and reprogramming of the cellular antioxidant system to cope with the ... -
Indian Herbs and their Therapeutic Potential against Alzheimer’s Disease and other Neurological Disorders
(Wiley, 2017)Many present-day diseases are caused by disruption of the delicate balance between the reactive oxygen/nitrogen species (ROS/RNS) produced by oxidants and their scavenging by the antioxidants in the body. Chief among them ... -
Phytochemical Ginkgolide B Attenuates Amyloid- 1 - 42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells
(IOS Press, 2017)Oxidative stress is an upsurge in reactive oxygen/nitrogen species (ROS/RNS), which aggravates damage to cellular components viz. lipids, proteins, and nucleic acids resulting in impaired cellular functions and neurological ... -
Understanding human thiol dioxygenase enzymes: structure to function and biology to pathology
(Wiley, 2017)Amino acid metabolism is a significant metabolic activity in humans, especially of sulphur-containing amino acids, methionine and cysteine (Cys). Cys is cytotoxic and neurotoxic in nature; hence, mammalian cells maintain ... -
Curcumin revitalizes Amyloid beta (25–35)-induced and organophosphate pesticides pestered neurotoxicity in SH-SY5Y and IMR-32 cells via activation of APE1 and Nrf2
(Springer, 2017)Amyloid beta (Aβ) peptide deposition is the primary cause of neurodegeneration in Alzheimer’s disease (AD) pathogenesis. Several reports point towards the role of pesticides in the AD pathogenesis, especially organophosphate ... -
Assessment of Antioxidant Potential of Dietary Components
(Elsevier, 2017)Antioxidants neutralize or mitigate the harmful effects of free radicals. Such antioxidants may be classed as either enzymatic or nonenzymatic. Some components in the diet act as important antioxidants as they may have ... -
Phytochemical Ginkgolide B Attenuates Amyloid-? amage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells
(IOS Press, 2017)Oxidative stress is an upsurge in reactive oxygen/nitrogen species (ROS/RNS), which aggravates damage to cellular components viz. lipids, proteins, and nucleic acids resulting in impaired cellular functions and neurological ... -
H 2 O 2 sensing through electrochemically deposited thionine coated ITO thin film
(Cellular and Molecular Biology Association, 2017)Progression and initiation of different diseases including pulmonary diseases, alzheimer's and tumors are linked with the oxidative stress, an important cause of cell damage. Different antioxidant enzymes are involved in ...