Browsing Zoology-Research Publications by Subject "ROS"
Now showing items 1-4 of 4
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APE1: A Molecule of Focus with Neuroprotective and Anti-Cancer Properties
(OMICS Publishing Group, 2013)Apurinic/Apyrimidinic endonuclease (APE1) is a multi-functional, central enzyme of base excision repair (BER) pathway that takes care of oxidized base damage (AP sites and strand breaks) caused by both endogenous and ... -
Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes.
(Springer, 2018)Maintaining genomic integrity is essential for cell survival and viability. Reactive oxygen species (ROS) overproduction results in oxidative stress leading to the genomic instability via generation of small base lesions ... -
Platelet-derived microvesicles activate human platelets via intracellular calcium mediated reactive oxygen species release
(Academic Press Inc., 2022-08-28)Platelet-derived microvesicles (PMVs) are the most abundant microvesicles in circulation, originating from blood platelets via membrane blebbing. PMVs act as biological cargo carrying key molecules from platelets, including ... -
Pseudomonas aeruginosa quorum sensing molecule N-3-oxo-dodecanoyl-Lhomoserine lactone activates human platelets through intracellular calciummediated ROS generation
(Elsevier, 2018)Pseudomonas aeruginosa, an opportunistic pathogen release N-3-oxo-dodecanoyl-l-homoserine lactone (3-oxo-C12HSL) and N-butyryl-l-homoserine lactone (C4-HSL) quorum sensing (QS) molecules to regulate various virulence factors ...