Now showing items 21-40 of 173

    • The incidence of male breast cancer: from fiction to reality - correspondence 

      Mukherjee, Anirban Goutam; Gopalakrishnan, Abilash Valsala; Jayaraj, Rama; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; Malik, Tabarak (NLM (Medline), 2023-05-24)
      [No abstract available]
    • Type 2 Diabetes (T2DM) and Parkinson�s Disease (PD): a Mechanistic Approach 

      Sabari, S. Sri; Balasubramani, Kiruthika; Iyer, Mahalaxmi; Sureshbabu, Harysh Winster; Venkatesan, Dhivya; Gopalakrishnan, Abilash Valsala; Narayanaswamy, Arul; Senthil Kumar, Nachimuthu; Vellingiri, Balachandar (Springer, 2023-04-28)
      Growing evidence suggest that there is a connection between Parkinson�s disease (PD) and insulin dysregulation in the brain, whilst the connection between PD and type 2 diabetes mellitus (T2DM) is still up for debate. ...
    • Evolving strategies and application of proteins and peptide therapeutics in cancer treatment 

      Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Gopalakrishnan, Abilash Valsala; Bradu, Pragya; Biswas, Antara; Ganesan, Raja; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; El Allali, Achraf; Alsamman, Alsamman M.; Zayed, Hatem; George Priya Doss, C. (Elsevier Masson s.r.l., 2023-05-05)
      Several proteins and peptides have therapeutic potential and can be used for cancer therapy. By binding to cell surface receptors and other indicators uniquely linked with or overexpressed on tumors compared to healthy ...
    • Advantages of mesenchymal stem cell over the other stem cells 

      Gopalarethinam, Janani; Nair, Aswathy P.; Iyer, Mahalaxmi; Vellingiri, Balachandar; Subramaniam, Mohana Devi (Elsevier GmbH, 2023-05-09)
      A stem cell is a particular group of cells that has the extraordinary potential to convert within the body into particular cell types. They are used to regenerate tissues and cells in the body that have been damaged or ...
    • Cloning, expression and in vitro validation of chimeric multi epitope vaccine candidate against visceral leishmaniasis infection 

      Ojha, Rupal; Chand, Kailash; Vellingiri, Balachandar; Prajapati, Vijay Kumar (Elsevier Inc., 2023-04-11)
      Visceral Leishmaniasis or Kala-Azar is one of the most severe and deadly neglected tropical disease caused by the Leishmania parasite. A few number of vaccines are going through different phases in clinical trial but failing ...
    • Surface modification of kevlar fabric with a novel sulfonyl aryl containing monomer and its influence on inter yarn friction 

      Agarwal, Gaurav; Sharma, Indu; Prakash, Jyoti; Kumar, Pal Dinesh; Verma, Sanjeev K (SAGE Publications Ltd, 2023-05-04)
      The ballistic impact response of Kevlar textiles is significantly influenced by the friction between the yarns. It increases the dissipation of energy when yarns begin to displace relative to one another and it also results ...
    • Concurrent Assessment of Oxidative Stress and MT-ATP6 Gene Profiling to Facilitate Diagnosis of Autism Spectrum Disorder (ASD) in Tamil Nadu Population 

      Vellingiri, Balachandar; Venkatesan, Dhivya; Iyer, Mahalaxmi; Mohan, Gomathi; Krishnan, Padmavathi; Sai Krishna, Krothapalli; Sangeetha, R.; Narayanasamy, Arul; Gopalakrishnan, Abilash Valsala; Kumar, Nachimuthu Senthil; Subramaniam, Mohana Devi (Springer, 2023-03-27)
      Autism spectrum disorder (ASD) is a neurodevelopmental disability that causes social impairment, debilitated verbal or nonverbal conversation, and restricted/repeated behavior. Recent research reveals that mitochondrial ...
    • Understanding Mutations in Human SARS-CoV-2 Spike Glycoprotein: A Systematic Review & Meta-Analysis 

      Kumar, Reetesh; Srivastava, Yogesh; Muthuramalingam, Pandiyan; Singh, Sunil Kumar; Verma, Geetika; Tiwari, Savitri; Tandel, Nikunj; Beura, Samir Kumar; Panigrahi, Abhishek Ramachandra; Maji, Somnath; Sharma, Prakriti; Rai, Pankaj Kumar; Prajapati, Dinesh Kumar; Shin, Hyunsuk; Tyagi, Rajeev K. (MDPI, 2023-03-28)
      Genetic variant(s) of concern (VoC) of SARS-CoV-2 have been emerging worldwide due to mutations in the gene encoding spike glycoprotein. We performed comprehensive analyses of spike protein mutations in the significant ...
    • Untangle the mystery behind DS-associated AD � Is APP the main protagonist? 

      Elangovan, Ajay; Babu, Harysh Winster Suresh; Iyer, Mahalaxmi; Gopalakrishnan, Abilash Valsala; Vellingiri, Balachandar (Elsevier Ireland Ltd, 2023-04-07)
      Amyloid precursor protein profusion in Trisomy 21, also called Down Syndrome (DS), is rooted in the genetic determination of Alzheimer's disease (AD). With the recent development in patient care, the life expectancy of DS ...
    • Nano-biotechnology in tumour and cancerous disease: A�perspective review 

      Soni, Ambikesh; Bhandari, Manohar Prasad; Tripathi, Gagan Kant; Bundela, Priyavand; Khiriya, Pradeep Kumar; Khare, Purnima Swarup; Kashyap, Manoj Kumar; Dey, Abhijit; Vellingiri, Balachandar; Sundaramurthy, Suresh; Suresh, Arisutha; P�rez�de�la�Lastra, Jos� M. (John Wiley and Sons Inc, 2023-02-25)
      In recent years, drug manufacturers and researchers have begun to consider the nanobiotechnology approach to improve the drug delivery system for tumour and cancer diseases. In this article, we review current strategies ...
    • Localization and expression of Orexin B (OXB) and its type 2 receptor (OX2R) in mouse testis during postnatal development 

      Yadav, Anupam; Singh, Shio Kumar; Sarkar, Debarshi (Elsevier Inc., 2023-02-24)
      The orexins (OXs) were first reported in hypothalamus of rat, and they play an important role in diverse physiological actions. The OXs consist of orexin A (OXA) and orexin B (OXB) peptides and their actions are mediated ...
    • The creation of selenium nanoparticles decorated with troxerutin and their ability to adapt to the tumour microenvironment have therapeutic implications for triple-negative breast cancer 

      Saranya, Thiruvenkataswamy; Kavithaa, Krishnamoorthy; Paulpandi, Manickam; Ramya, Sennimalai; Winster, Sureshbabu Harysh; Mani, Geetha; Dhayalan, Sangeetha; Balachandar, Vellingiri; Narayanasamy, Arul (Royal Society of Chemistry, 2023-02-09)
      Despite advancements in treatment, managing aggressive types of breast cancer, particularly Triple Negative Breast Cancer (TNBC), remains a daunting task. Newer chemotherapeutics enhance the multidrug resistance in cancer ...
    • A Systematic Role of Metabolomics, Metabolic Pathways, and Chemical Metabolism in Lung Cancer 

      Kannampuzha, Sandra; Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Gopalakrishnan, Abilash Valsala; Murali, Reshma; Namachivayam, Arunraj; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; Madhyastha, Harishkumar; Ganesan, Raja (MDPI, 2023-02-08)
      Lung cancer (LC) is considered as one of the leading causes of cancer-associated mortalities. Cancer cells� reprogrammed metabolism results in changes in metabolite concentrations, which can be utilized to identify a ...
    • Insights into the Scenario of SARS-CoV-2 Infection in Male Reproductive Toxicity 

      Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Gopalakrishnan, Abilash Valsala; Kannampuzha, Sandra; Murali, Reshma; Namachivayam, Arunraj; Ganesan, Raja; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; Prabakaran, D.S. (MDPI, 2023-02-23)
      COVID-19 has become a significant public health concern that has catastrophic consequences for society. Some preliminary evidence suggests that the male reproductive system may be an infection target for SARS-CoV-2. ...
    • Bioactive peptides for boosting stem cell culture platform: Methods and applications 

      Abdal Dayem, Ahmed; Lee, Soo Bin; Lim, Kyung Min; Kim, Aram; Shin, Hyun Jin; Vellingiri, Balachandar; Kim, Young Bong; Cho, Ssang-Goo (Elsevier Masson s.r.l., 2023-02-09)
      Peptides, short protein fragments, can emulate the functions of their full-length native counterparts. Peptides are considered potent recombinant protein alternatives due to their specificity, high stability, low production ...
    • The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review 

      Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Kannampuzha, Sandra; Murali, Reshma; Namachivayam, Arunraj; Ganesan, Raja; Dey, Abhijit; Babu, Achsha; Renu, Kaviyarasi; Vellingiri, Balachandar; Ramanathan, Gnanasambandan; George Priya Doss, C.; Elsherbiny, Nehal; Elsherbini, Amira M.; Alsamman, Alsamman M.; Zayed, Hatem; Gopalakrishnan, Abilash Valsala (MDPI, 2023-01-16)
      As a complex endocrine and metabolic condition, polycystic ovarian syndrome (PCOS) affects women�s reproductive health. These common symptoms include hirsutism, hyperandrogenism, ovulatory dysfunction, irregular menstruation, ...
    • Heavy Metal and Metalloid Contamination in Food and Emerging Technologies for Its Detection 

      Mukherjee, Anirban Goutam; Renu, Kaviyarasi; Gopalakrishnan, Abilash Valsala; Veeraraghavan, Vishnu Priya; Vinayagam, Sathishkumar; Paz-Montelongo, Soraya; Dey, Abhijit; Vellingiri, Balachandar; George, Alex; Madhyastha, Harishkumar; Ganesan, Raja (Multidisciplinary Digital Publishing Institute (MDPI), 2023-01-09)
      Heavy metal and metalloid poisoning in the environment and food has piqued the public�s interest since it poses significant hazards to the ecological system and human health. In food, several metals, including cadmium (Cd), ...
    • Role of Metabolism and Metabolic Pathways in Prostate Cancer 

      Wanjari, Uddesh Ramesh; Mukherjee, Anirban Goutam; Gopalakrishnan, Abilash Valsala; Murali, Reshma; Dey, Abhijit; Vellingiri, Balachandar; Ganesan, Raja (MDPI, 2023-01-26)
      Prostate cancer (PCa) is the common cause of death in men. The pathophysiological factors contributing to PCa are not well known. PCa cells gain a protective mechanism via abnormal lipid signaling and metabolism. PCa cells ...
    • Exploring the Molecular Pathogenesis, Pathogen Association, and Therapeutic Strategies against HPV Infection 

      Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Gopalakrishnan, Abilash Valsala; Kannampuzha, Sandra; Murali, Reshma; Namachivayam, Arunraj; Ganesan, Raja; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; Prabakaran, D.S. (MDPI, 2022-12-27)
      The human papillomavirus (HPV), commonly documented as the cause of warts, has gained much interest recently due to its possible links to several types of cancer. HPV infection is discussed in this review from multiple ...
    • Rest of the carpenter ant�Camponotus compressus�undergoes a drastic change after mating 

      Lone, S.R. (Springer Science and Business Media Deutschland GmbH, 2023-01-04)
      Studies on many species have suggested that animals across the taxa remain behaviourally motionless for a significant part of their active phase. It is true of social insects such as ants, which constitute a considerable ...