Chemical Sciences-Research Publications
Recent Submissions
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Morpholine substituted quinazoline derivatives as anticancer agents against MCF-7, A549 and SHSY-5Y cancer cell lines and mechanistic studies
(Royal Society of Chemistry, 2022)A series of morpholine substituted quinazoline derivatives have been synthesized and evaluated for cytotoxic potential against A549, MCF-7 and SHSY-5Y cancer cell lines. These compounds were found to be non-toxic against ... -
Synergistic effect of eco-friendly pistachio shell biomass on nano-MnO2 for crystal violet removal: kinetic and equilibrium studies
(Springer, 2022)Pistachio shell powder-supported MnO2 nanostructure-based eco-friendly nanocomposite (nMPP) was prepared via one-pot redox precipitation method and was characterized by FTIR, XRD, SEM, TEM, BET, TGA/DTA, and XPS techniques. ... -
Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer’s Disease
(Bentham Science Publishers, 2022)Alzheimer’s disease (AD) is a complex neurological disorder and multiple pathological factors are believed to be involved in the genesis and progression of the disease. A number of hypothesis including Acetylcholinesterase, ... -
Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease
(Elsevier, 2022)Alzheimer's disease (AD) is a multifactorial irreversible neurological disorder which results in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and neuronal death. Exact pathology of ... -
Synthesis of in situ immobilized iron oxide nanoparticles (Fe3O4) on microcrystalline cellulose: Ecofriendly and recyclable catalyst for Michael addition
(Wiley, 2022)Microcrystalline cellulose-immobilized Fe3O4 magnetic nanoparticles (Fe3O4@MCC) with iron loading 5%–20% are synthesized and characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and thermogravimetric ... -
Genomic DNA-mediated formation of a porous Cu2(OH)PO4/Co3(PO4)2·8H2O rolling pin shape bifunctional electrocatalyst for water splitting reactions
(Royal Society of Chemistry, 2022)Among the accessible techniques, the production of hydrogen by electrocatalytic water oxidation is the most established process, which comprises oxygen evolution reaction (OER) and hydrogen evolution reaction (HER). Here, ... -
KI-assisted Sulfur Activation/Insertion/Denitration Strategy towards Dual C−S Bond Formation for One-pot Synthesis of β-Carboline-tethered 2-Acylbenzothiophenes
(Wiley, 2022)A simple and efficient KI promoted sulfur activation-insertion/de-nitration strategy has been developed for the synthesis of β-carboline C1 tethered 2-acylbenzothiophenes via one-pot assembly of 1-acetyl β-carbolines (an ... -
Molecular characterization and differential expression of an aromatic heptaketide producing type III plant polyketide synthase from Himalayan rhubarb
(Springer, 2022)Rheum australe (Himalayan Rhubarb, Polygonaceae), an endangered medicinal and vegetable herb owes its age-old remedying properties to the bio-active phyto-constituents viz. anthraquinones, stilbenoids, chromones and dietary ... -
Sustainable synthesis of highly diastereoselective & fluorescent active spirooxindoles catalyzed by copper oxide nanoparticle immobilized on microcrystalline cellulose
(Wiley, 2022)Composites of copper oxide nanoparticles immobilized on microcrystalline cellulose (Cu2O@MCC) were synthesized and studied for their catalytic activity toward 1,3-dipolar cycloaddition reaction. Azomethine ylide was in ... -
Design, synthesis, and biological evaluation of N-[1-(6′-chloropyridazin-3′-yl)-3-(4″-substitutedphenyl)-1H-pyrazole-5-yl]alkanamides as anti-inflammatory agents
(Wiley, 2022)A series of structurally diverse N-[1-(6′-chloropyridazin-3′-yl)-3-(4″-substitutedphenyl)-1H-pyrazole-5-yl]alkanamides 5(a–r) has been designed and synthesized via Aliquat 336 catalyzed amidation of 5-amino-3-aryl-1-(6′- ... -
DNA Origami-Templated Bimetallic Core-Shell Nanostructures for Enhanced Oxygen Evolution Reaction
(American Chemical Society, 2022)Hydrogen generation through electrocatalytic water splitting offers promising technology for sustainable and clean energy production as an alternative to conventional energy sources. The development of highly active ... -
Dumbbell-Shaped Ternary Transition-Metal (Cu, Ni, Co) Phosphate Bundles: A Promising Catalyst for the Oxygen Evolution Reaction
(Amer Chemical Soc, 2022)Development of economical and high-performance electrocatalysts for the oxygen evolution reaction (OER) is of tremendous interest for future applications as sustainable energy materials. Here, a unique member of efficient ... -
Green Synthesis of Bimetallic Au/Ag Nanostructures Using Aqueous Extract of Eichhornia crassipes for Antibacterial Activity
(Springer, 2022)Biosynthesis of nanostructured materials is an arising feature of the interdisciplinary relationship between nanotechnology and biotechnology and acquiring consideration because of developing interest to foster ecologically ... -
Genomic DNA-mediated formation of a porous Cu-2(OH)PO4/Co-3(PO4)(2)center dot 8H(2)O rolling pin shape bifunctional electrocatalyst for water splitting reactions
(Royal Soc Chemistry, 2022)Among the accessible techniques, the production of hydrogen by electrocatalytic water oxidation is the most established process, which comprises oxygen evolution reaction (OER) and hydrogen evolution reaction (HER). Here, ... -
Green Approach for the Fabrication of Au/ZnO Nanoflowers: A Catalytic Aspect
(American Chemical Society, 2021)An easy, environmentally benign, and biomimetic approach employing Azadirachta indica (neem) leaf extract as a reducing as well as capping agent was used for the fabrication of gold (Au)/zinc oxide (ZnO) hybrid nanoflowers ... -
A dual stimuli responsive natural polymer based superabsorbent hydrogel engineered through a novel cross-linker
(Royal Society of Chemistry, 2021)Natural protein-based polymers may serve as a potential source for developing advanced porous organic macromolecules, possessing exquisite control over the pores, which impart exceptional properties to these materials. ... -
Tah1, A Key Component of R2TP Complex that Regulates Assembly of snoRNP, is Involved in De Novo Generation and Maintenance of Yeast Prion [URE3]
(Academic Press, 2021)The cellular chaperone machinery plays key role in the de novo formation and propagation of yeast prions (infectious protein). Though the role of Hsp70s in the prion maintenance is well studied, how Hsp90 chaperone machinery ... -
Effect of oxygen vacancies, lattice distortions and secondary phase on the structural, optical, dielectric and ferroelectric properties in Cd-doped Bi2Ti2O7 nanoparticles
(Elsevier, 2021)(Bi1-xCdx)2Ti2O7 (x = 0.00, 0.02, 0.04, 0.06, 0.08, 0.10 and 0.12) nanoparticles are synthesised using the co-precipitation method. The prepared samples show pyrochlore phase formation except for x = 0.02 and 0.08, where ... -
Effect of imidazolium based ionic liquids on CO-association dynamics and thermodynamic stability of Ferrocytochrome c
(Elsevier, 2021)Analysis of kinetic and thermodynamic parameters measured for CO-association reaction of Ferrocytochrome c (Ferrocyt c) under variable concentrations of 1-butyl-3-methylimidazolium with varying anion ([Bmim]X) (X = Cl?, ... -
P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds
(Wiley-VCH Verlag, 2021)A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. ...