Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Title
Now showing items 270-272 of 272
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Virtual screening and molecular dynamics simulation approach for the identification of potential multi-target directed ligands for the treatment of Alzheimer�s disease
(Taylor and Francis Ltd., 2023-04-28)Alzheimer�s disease (AD) is a multifactorial neurological disorder characterized by memory loss and cognitive impairment. The currently available single-targeting drugs have miserably failed in the treatment of AD, and ... -
Virtual screening, structure based pharmacophore mapping, and molecular simulation studies of pyrido[2,3-d]pyrimidines as selective thymidylate synthase inhibitors
(Taylor and Francis Ltd., 2023-05-08)Human thymidylate synthase is the rate-limiting enzyme in the de novo synthesis of 2'-deoxythymidine-5'-monophosphate. dUMP (pyrimidine) and folate binding site hTS inhibitors showed resistance in colorectal cancer (CRC). ... -
X-ray fluorescence: Current trends and future scope
(wiley, 2022-04-15)X-ray fluorescence is a non-destructive research technique, which is used to assess a material's chemical composition. Many early X-ray fluorescence imaging (XFI) research projects in live systems have used plants. Early ...
