Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Subject "Aromatase"
Now showing items 1-5 of 5
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Medicinal chemistry aspects and synthetic strategies of coumarin as aromatase inhibitors: an overview
(Springer, 2022-12-05)Coumarin is a bicyclic oxygen bearing heterocyclic scaffold formed by fusion of benzene with the pyrone ring. Because of its unique physicochemical characteristics and the ease with which it may be transformed into a wide ... -
Multitargeted molecular docking study of natural-derived alkaloids on breast cancer pathway components
(Bentham Science Publishers B.V., 2017)Background: Targeting of multiple sites is a pharmacologically, pharmacokinetic and dynamically more acceptable approach for complex diseases such as BC. It is recommended that the women who are at high risk of developing ... -
Polymeric nanoparticles of aromatase inhibitors: A comprehensive review
(Bentham Science Publishers, 2020-09-29)Being the second most frequent cancer, breast cancer is emerging worldwide with an alarming rate, specifically in post-menopausal women. Targeted drug delivery has been in the focus for the successful treatment of breast ... -
Recent development in indole derivatives as anticancer agent: A mechanistic approach
(Bentham Science Publishers, 2021-01-05)Background: Cancer accounts for several deaths each year. There are multiple FDA approved drugs for cancer treatments. Due to the severe side effects and multiple drug resistance, the current drug therapies become ineffective. ... -
Selective Estrogen receptor degraders (SERDs) for the treatment of breast cancer: An overview
(Elsevier Masson s.r.l., 2023-05-04)Discovery of SERDs has changed the direction of anticancer research, as more than 70% of breast cancer cases are estrogen receptor positive (ER+). Therapies such as selective estrogen receptor modulators (SERM) and aromatase ...