Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Subject "Chemical Structure"
Now showing items 1-2 of 2
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Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives
(Elsevier Ltd, 2016)The metabotropic glutamate receptors (mGlu receptors) have emerged as attractive targets for number of neurological and psychiatric disorders. Recently, mGluR5 negative allosteric modulators (NAMs) have gained considerable ... -
Pyrazoloquinazolines: Synthetic strategies and bioactivities
(2015)Numerous N-heterocycles are indisputably evidenced to exhibit myriad biological activities. In the recent past, attempts made to condense the various heterocycles have resulted in derivatives possessing better bioactivities. ...