Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Subject "Diabetes mellitus"
Now showing items 1-3 of 3
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Research progress on 2,4-thiazolidinedione and 2-thioxo-4-thiazolidinone analogues as aldose reductase inhibitors
(Elsevier B.V., 2022-07-18)Diabetes-associated complications are a major global health concern. In diabetics, the increased accumulation of sorbitol, produced via over activated polyol pathway, from glucose by the action of aldose reductase (AR, ... -
A Review on Molecular Mechanism of Flavonoids as Antidiabetic Agents
(Bentham Science, 2019)The development of drugs possessing anti-diabetic activities is a long pursued goal in drug discovery. It has been shown that deregulated insulin mediated signaling, oxidative stress, obesity, and β-cell dysfunction are ... -
Structure-based Virtual Screening and Molecular Dynamic Simulation Approach for the Identification of Terpenoids as Potential DPP-4 Inhibitors
(Bentham Science Publishers, 2023-05-16)Background: Diabetes mellitus is a metabolic disorder where insulin secretion is compromised, leading to hyperglycemia. DPP-4 is a viable and safer target for type 2 diabetes mellitus. Computational tools have proven to ...