Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Subject "Drug"

Now showing items 1-2 of 2

    • FDA approved fused pyrimidine-based drugs 

      Thakur, Shikha; Ansari, Arshad J.; Joshi, Gaurav (Elsevier, 2022-10-14)
      The present chapter is a compilation and analysis of USFDA approved small drug candidates about fused pyrimidine pharmacophore. Out of 63 drugs approved so far, nearly 38% of drugs are approved for chemotherapeutic treatment ...

    • Toxicophore exploration as a screening technology for drug design and discovery: techniques, scope and limitations 

      Singh, Pankaj Kumar; Negi, Arvind; Gupta, Pawan Kumar; Chauhan, Monika; Kumar, Raj (Springer Verlag, 2016)
      Toxicity is a common drawback of newly designed chemotherapeutic agents. With the exception of pharmacophore-induced toxicity (lack of selectivity at higher concentrations of a drug), the toxicity due to chemotherapeutic ...