Browsing Pharmaceutical Sciences and Natural Products-Research Publications by Subject "Insulin resistance"
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Rational design and synthesis of novel biphenyl thiazolidinedione conjugates as inhibitors of protein tyrosine phosphatase 1B for the management of type 2 diabetes
(Elsevier B.V., 2022-11-12)To achieve the unmet discovery of protein tyrosine phosphatase 1B (PTP1B) inhibitors, we have rationally designed novel biphenyl thiazolidinedione conjugates (8a-n). The designed molecules were found fit on in silico ... -
A Review on Molecular Mechanism of Flavonoids as Antidiabetic Agents
(Bentham Science, 2019)The development of drugs possessing anti-diabetic activities is a long pursued goal in drug discovery. It has been shown that deregulated insulin mediated signaling, oxidative stress, obesity, and β-cell dysfunction are ...