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Ganoderic acid, lanostanoid triterpene: a key player in apoptosis
(Springer New York LLC, 2018)
Cancer is a multifactorial disease, causing behavioral and metabolic alterations, leading to uncontrolled cell proliferation with collateral weakening of immune system. Crucial balance between cell proliferation and cell ...
Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer
(Springer Netherlands, 2016)
Evaluating anti-oxidant potential of Ganoderic acid A in STAT 3 pathway in Prostate cancer. Molecular docking and ADMET activities of different isoforms of ganoderic acid on STAT 3 pathway were performed by Maestro 9.6 ...
Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer
(Sage, 2017)
Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and ...
Missing link between microRNA and prostate cancer
(Springer Netherlands, 2016)
MicroRNAs are the non-coding RNAs which regulate endogenous gene expression in animal and plant cells. Alterations in the level of micro-ribonucleic acids (miRNAs) involving the deletions, overexpression, mutations, ...
Misconstrued versatility of Ganoderma lucidum: a key player in multi-targeted cellular signaling
(Springer, 2016)
A Basidiomycetes fungus belonging to polypore family of mushrooms, Ganoderma lucidum (GL), has been known since a long time for their myriad therapeutic indications. Renowned as an invaluable resource of cardinal ...
Drought and heat tolerance in chickpea: Transcriptome and morphophysiological changes under individual and combined stress
(Springer India, 2017)
Increase in global temperature due to climate change is the major concern and known to have detrimental effect on many agricultural crops. Chickpea (Cicer arietinum L.) is an important legume grown in the arid and semiarid ...
Temperature-stratified screening of chickpea (Cicer arietinum L.) genetic resource collections reveals very limited reproductive chilling tolerance compared to its annual wild relatives
(2012)
Low reproductive chilling tolerance in chickpea impairs ovule fertilization, delaying pod set, exposing the crop to terminal drought throughout much of its distribution range. Despite this realization, little progress has ...
Ganoderic Acid A Targeting β-Catenin in Wnt Signaling Pathway: In Silico and In Vitro Study
(Springer, 2016)
Wnt signaling pathways are the group of signaling transduction controlling the embryonic development, cell proliferation, cell migration, cell fate specification, and body axis pattern. Nuclear accumulation of β-catenin ...
Ganoderma lucidum targeting lung cancer signaling: A review
(SAGE Publications Ltd, 2017)
Lung cancer causes huge mortality to population, and pharmaceutical companies require new drugs as an alternative either synthetic or natural targeting lung cancer. The conventional therapies cause side effects, and ...
Ganoderic acid modulating TNF and its receptors: in silico and in vitro study
(Springer, 2017)
Cancer is a multifactorial disease with a network of genes causing genetic alterations. The sophisticated techniques in molecular biology revealed different cancer pathway, but their mechanistic approach is still shrouded. ...