Browsing Human Genetics and Molecular Medicine-Research Publications by Subject "Trastuzumab"
Now showing items 1-2 of 2
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Genomic alterations associated with HER2+ breast cancer risk and clinical outcome in response to trastuzumab
(Springer, 2019)Human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BC) is an aggressive BC subtype characterized by HER2 overexpression/amplification. Genomic alterations of HER2 and others have been reported to be ... -
Recent advances in HER2 positive breast cancer epigenetics: Susceptibility and therapeutic strategies
(Elsevier Masson SAS, 2017)HER2 amplification/overexpression accounts for aggressive clinical features of HER2 positive breast cancer. Epigenetic changes including DNA methylation, histone modifications and ncRNAs/miRNAs are associated with regulation ...