Browsing Human Genetics and Molecular Medicine-Research Publications by Subject "miRNAs"
Now showing items 1-4 of 4
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ACE-Triggered Hypertension Incites Stroke: Genetic, Molecular, and Therapeutic Aspects
(Springer, 2019)Stroke is the second largest cause of death worldwide. Angiotensin converting enzyme (ACE) gene has emerged as an important player in the pathogenesis of hypertension and consequently stroke. It encodes ACE enzyme that ... -
miRNA signatures in diabetic retinopathy and nephropathy: delineating underlying mechanisms
(Springer Science and Business Media B.V., 2022-01-31)A worldwide failure to achieve glycemic targets has led to complications associated with diabetes mellitus. In addition to genetic and other risk factors, epigenetic factors like DNA methylation, histone modifications, and ... -
Role of miRNAs in diabetic neuropathy: mechanisms and possible interventions
(Springer, 2022-01-13)Accelerating cases of diabetes worldwide have given rise to higher incidences of diabetic complications. MiRNAs, a much-explored class of non-coding RNAs, play a significant role in the pathogenesis of diabetes mellitus ... -
Small regulatory molecules acting big in cancer: Potential role of mito-miRs in cancer
(Bentham Science Publishers, 2019)MicroRNAs [miRNAs] are short, non-coding, single stranded RNA molecules regulating gene expression of their targets at the posttranscriptional level by either degrading mRNA or by inhibiting translation. Previously, miRNAs ...