Browsing Zoology-Master Dissertation by Submit Date
Now showing items 1-12 of 12
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Role of curcumin on monoamine oxidase(MAO) enzyme expression and activity against Amyloid Beta (A?)-induced oxidative stress in human glioblastoma U-87 MG cell.
(Central University of Punjab, 2018)Glioblastoma (GBM) is the most common brain tumor in humans. The major factor responsible for its progression is oxidative stress. Oxidative stress leads to disruption of signaling pathways and damage to cells and tissues. ... -
Development of lactadherin based electrochemical biosensor for the detection of platelet microvesicles
(Central University of Punjab, 2018)Platelet derived microvesicles (PMVs) are the most abundant membrane vesicles in the blood having a potent pro-inflammatory effect, promote coagulation and affect vascular function which are involved in the pathogenesis ... -
Expression Study of Long non-coding RNA SCAL1 and GAS6-AS1 in Lung cancer Cell line A549 Compared to IMR-90
(Central University of Punjab, 2018)Lung cancer is the fatal type of cancer owing to maximum number death worldwide. Despite the advances in clinical and experimental setup lung cancer still is the deadliest type of cancer wherein survival rate is as low as ... -
To Study the Anti-Proliferative Effect of Pirfenidone via MAP Kinase Signaling Pathway
(Central University of Punjab, 2018)Pirfenidone is a pyridine chemical compound used as a therapeutic drug used for the treatment of Idiopathic Pulmonary Fibrosis (IPF). The characteristic feature of the fibrosis is the deposition of extracellular matrix ... -
To check the glioprotective effect of Withaferin A on C6 Glioma cell Culture challenged with Kainic Acid
(Central University of Punjab, 2018)Last many years perception of glial cell function in CNS has been changed. In fact abnormalities in glial cells also contribute to various disorders. Glutamate induced excitotoxicity attributed to various CNS related ... -
Neuro-Protective Role Of Ginkgolide B In A?induced Neurodegeneration And Ache Enzyme Activity In Human Neuroblastoma Sh-Sy5Y Cells
(Central University of Punjab, 2018)Ginkgolide B (GB) is being used as medicine in China for treating neurodegenerative diseases for a long time. Its neuroprotective role is getting well established. Alzheimer's disease (AD) is a neurodegenerative disease ... -
Expression analysis of long non-coding RNA GAS5 and BANCR in lung cancer cell line A549 compared to IMR-90.
(Central University of Punjab, 2018)Lung cancer is the major cause of death worldwide. Several chemotherapeutic drugs and therapies have been established, but the early diagnosis and prognosis of lung cancer is still a question. Long non-coding RNAs are ... -
To Test The Role Of Withaferin A In Neuroprotection On Sh-Sy5Y Cell Line Challenged By Kainic Acid
(Central University of Punjab, 2018)Withania somnifera (WS) has been used in traditional medicine for a variety of neural disorders. Recently, chronic neurodegenerative conditions have been shown to benefit from treatment with this crude extract. Neurotoxicity ... -
Isolation and characterization of platelet microvesicles
(Central University of Punjab, 2018)In the recent years, Platelet microvesicles (PMVs) are projected as potential diagnostic and prognostic biomarkers of many diseases like cardiovascular diseases, diabetes and infection. Due to the small size (100-1000 nm), ... -
Traumatic Brain Injury (TBI) causes hypersomnia in Drosophila melanogaster
(Central University of Punjab, 2018)Traumatic brain injury (TBI) is one of the deadly event which is a leading cause of neurological impairments and loss of life. The TBI outcomes arise from primary and secondary injuries. It damages neurons as well as causes ... -
Role of midgut digestive proteases upon sub-lethal exposure of Cry toxin in the larvae of castor semilooper, Achaea janata
(Central University of Punjab, 2018)Development of synthetic insecticides to reduce the level of infestation led to deleterious effects on the environment and human health. This lead to the development of eco-friendly pest management alternatives including ... -
Oxidative stress responses to sub-lethal dose of Cry toxin in the larvae of castor semilooper, Achaea janata
(Central University of Punjab, 2018)Development of synthetic insecticides to reduce the level of infestation led to deleterious effects on environment and human health. This lead to the development of ecofriendly pest management alternatives including Bacillus ...