Browsing Pharmaceutical Sciences and Natural Products-Master Dissertation by Author "Kumar, Raj"
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Anticancer potential of new n-acetyl pyrazoline derivatives of 1,3 diaryl/hetroaryl propenoes: Synethesis and evaluation
Alex, Jimi Martin (Central University of Punjab, 2013)Pyrazoles, categorized as nitrogen-containing heterocycles, are well known for their interminable participation in the field of perpetual research and development of therapeutical active agents. As a consequence pyrazoles ... -
Antiproliferative Activity of Chloroform and Methanol Extracts of Piper attenuatum (Buch-Ham)
Pathak, Neha (Central University of Punjab, 2018)Indian traditional medicinal plant Piper attenuatum (Buch-Ham) has been investigated for its antiproliferative activity. Dried powder of fruits of Piper attenuatum (Buch-Ham) was subjected to maceration to prepare various ... -
Design and synethesis of APE1 inhibitors as putative anticancer agents
Kaur, Gagandeep (Central University of Punjab, 2014)Success in chemotherapy has not been attained completely yet and has remained a worried issue from years. Various reasons drive this failure, but the much talked about is failure due to emergence of resistance to ... -
Imidazole based compunds: Synethesis and in vitro anticancer screening
Negi, Arvind (Central University of Punjab, 2013)Imidazole is an important five-membered aromatic heterocycle widely present in natural products and synthetic molecules. The unique structural feature of imidazole ring with desirable electron rich characteristic is ... -
Synethesis and biochemical screening of novel non-purine based xanthine oxidase inhibitors
Kumar, Deependra (Central University of Punjab, 2013)Xanthine oxidase (XO), or xanthine oxidoreductase (XOR), is a complex molybdoflavoenzyme which, in humans, is recognized as the terminal enzyme of purine catabolism, catalysing the hydroxylation of purines to uric acid, ... -
Synthesis And Antiproliferative Activity Of Pyrazole-Based Heterocycles
Pandey, Vishakha (Central University of Punjab, 2018)Among the various heterocyclic compounds pyrazole and its derivatives have occupied wide range of biological and pharmacological activities. These were observed for their modes of function in the inhibition of topoisomerase ... -
Synthesis, Characterization and Biological Evaluation of 5-(2- Nitrophenyl)-1H-Pyrazole Derivatives as Putative Antiproliferative Agents
Saini, Geetika (Central University of Punjab, 2018)Pyrazoles are known to exhibit various biological activities like antibacterial, antiprotozoal, anticonvulsant, analgesic, anti-inflammatory, antiviral and antiproliferative. An attempt has been made to synthesize substituted ...