Browsing Pharmaceutical Sciences and Natural Products-Master Dissertation by Author "Kumar, Vinod"
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3-D QSAR Study Of Combretastatins Fused With Hetrocyclic Ring As Tubulin Binding Agents
Dhanka, Ajit Kumar (Central University of Punjab, 2018)Combretastatin A4 (CA4) is a leading agent in vascular disrupting strategies and tubulin polymerization inhibitor for the tumour therapy. A large number of combretastatin derivatives have been synthesized as potent ... -
Design and synethesis of putative anti-cancer agents using hybrid molecular approach
Saini, Vijayinder (Central University of Punjab, 2014)A Hybrid drug involves the unification of two drug pharmacophores in one single molecule. The hybrid drugs are designed to interact with multiple targets or to intensify its effect through action on another bio target as ... -
Synthesis And Biological Evaluation Of Pyrimidine Bridged Biphenyls As Putative Ligands To Target Parkinson's Disease
Bala, Manu (Central University of Punjab, 2018)MAO inhibitors have been explored as therapeutic agents for the treatment or management of PD. A series of 2,4,6-trisubstituted pyrimidine derivatives incorporating a propargyl moiety were synthesized and screened for their ...